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Patient-derived ovarian cancer organoids capture the genomic profiles of primary tumours applicable for drug sensitivity and resistance testing
The use of primary patient-derived organoids for drug sensitivity and resistance testing could play an important role in precision cancer medicine. We developed expandable ovarian cancer organoids in < 3 weeks; these organoids captured the characteristics of histological cancer subtypes and repli...
Autores principales: | Nanki, Yoshiko, Chiyoda, Tatsuyuki, Hirasawa, Akira, Ookubo, Aki, Itoh, Manabu, Ueno, Masaru, Akahane, Tomoko, Kameyama, Kaori, Yamagami, Wataru, Kataoka, Fumio, Aoki, Daisuke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387538/ https://www.ncbi.nlm.nih.gov/pubmed/32724113 http://dx.doi.org/10.1038/s41598-020-69488-9 |
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