Mechanisms of microtubule dynamics and force generation examined with computational modeling and electron cryotomography

Microtubules are dynamic tubulin polymers responsible for many cellular processes, including the capture and segregation of chromosomes during mitosis. In contrast to textbook models of tubulin self-assembly, we have recently demonstrated that microtubules elongate by addition of bent guanosine trip...

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Detalles Bibliográficos
Autores principales: Gudimchuk, Nikita B., Ulyanov, Evgeni V., O’Toole, Eileen, Page, Cynthia L., Vinogradov, Dmitrii S., Morgan, Garry, Li, Gabriella, Moore, Jeffrey K., Szczesna, Ewa, Roll-Mecak, Antonina, Ataullakhanov, Fazoil I., Richard McIntosh, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387542/
https://www.ncbi.nlm.nih.gov/pubmed/32724196
http://dx.doi.org/10.1038/s41467-020-17553-2

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