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Extracellular gp96 is a crucial mediator for driving immune hyperactivation and liver damage

Liver failure leads to the massive necrosis of hepatocytes, releasing large amounts of intracellular components including damage-associated molecular patterns (DAMPs). We found that extracellular gp96 levels in serum were elevated in patients with chronic hepatitis B infection (CHB) and acute-on-chr...

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Detalles Bibliográficos
Autores principales:	Guan, Zeliang, Ding, Yun, Liu, Yongai, Zhang, Yu, Zhao, Jingmin, Li, Changfei, Li, Zihai, Meng, Songdong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387550/ https://www.ncbi.nlm.nih.gov/pubmed/32724151 http://dx.doi.org/10.1038/s41598-020-69517-7

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