Endothelial Cell Dynamics in Vascular Development: Insights From Live-Imaging in Zebrafish

The formation of the vertebrate vasculature involves the acquisition of endothelial cell identities, sprouting, migration, remodeling and maturation of functional vessel networks. To understand the cellular and molecular processes that drive vascular development, live-imaging of dynamic cellular eve...

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Detalles Bibliográficos
Autores principales: Okuda, Kazuhide S., Hogan, Benjamin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387577/
https://www.ncbi.nlm.nih.gov/pubmed/32792978
http://dx.doi.org/10.3389/fphys.2020.00842
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author Okuda, Kazuhide S.
Hogan, Benjamin M.
author_facet Okuda, Kazuhide S.
Hogan, Benjamin M.
author_sort Okuda, Kazuhide S.
collection PubMed
description The formation of the vertebrate vasculature involves the acquisition of endothelial cell identities, sprouting, migration, remodeling and maturation of functional vessel networks. To understand the cellular and molecular processes that drive vascular development, live-imaging of dynamic cellular events in the zebrafish embryo have proven highly informative. This review focusses on recent advances, new tools and new insights from imaging studies in vascular cell biology using zebrafish as a model system.
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spelling pubmed-73875772020-08-12 Endothelial Cell Dynamics in Vascular Development: Insights From Live-Imaging in Zebrafish Okuda, Kazuhide S. Hogan, Benjamin M. Front Physiol Physiology The formation of the vertebrate vasculature involves the acquisition of endothelial cell identities, sprouting, migration, remodeling and maturation of functional vessel networks. To understand the cellular and molecular processes that drive vascular development, live-imaging of dynamic cellular events in the zebrafish embryo have proven highly informative. This review focusses on recent advances, new tools and new insights from imaging studies in vascular cell biology using zebrafish as a model system. Frontiers Media S.A. 2020-07-22 /pmc/articles/PMC7387577/ /pubmed/32792978 http://dx.doi.org/10.3389/fphys.2020.00842 Text en Copyright © 2020 Okuda and Hogan. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Physiology
Okuda, Kazuhide S.
Hogan, Benjamin M.
Endothelial Cell Dynamics in Vascular Development: Insights From Live-Imaging in Zebrafish
title Endothelial Cell Dynamics in Vascular Development: Insights From Live-Imaging in Zebrafish
title_full Endothelial Cell Dynamics in Vascular Development: Insights From Live-Imaging in Zebrafish
title_fullStr Endothelial Cell Dynamics in Vascular Development: Insights From Live-Imaging in Zebrafish
title_full_unstemmed Endothelial Cell Dynamics in Vascular Development: Insights From Live-Imaging in Zebrafish
title_short Endothelial Cell Dynamics in Vascular Development: Insights From Live-Imaging in Zebrafish
title_sort endothelial cell dynamics in vascular development: insights from live-imaging in zebrafish
topic Physiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387577/
https://www.ncbi.nlm.nih.gov/pubmed/32792978
http://dx.doi.org/10.3389/fphys.2020.00842
work_keys_str_mv AT okudakazuhides endothelialcelldynamicsinvasculardevelopmentinsightsfromliveimaginginzebrafish
AT hoganbenjaminm endothelialcelldynamicsinvasculardevelopmentinsightsfromliveimaginginzebrafish

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