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Newly Diagnosed Sarcopenia and Alzheimer’s Disease in an Older Patient With Chronic Inflammation

A 78-year-old man presented with the aggravation of weakness in the lower extremities, gait disturbance, and cognitive impairment. He was diagnosed with sarcopenia, distal sensorimotor polyneuropathy, and Alzheimer’s disease. Low-grade chronic elevation of inflammatory markers was also revealed. We...

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Detalles Bibliográficos
Autores principales: Kim, Sun-Hyung, Sin, Deok Su, Lim, Jae-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Geriatrics Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387604/
https://www.ncbi.nlm.nih.gov/pubmed/32743285
http://dx.doi.org/10.4235/agmr.19.0005
Descripción
Sumario:A 78-year-old man presented with the aggravation of weakness in the lower extremities, gait disturbance, and cognitive impairment. He was diagnosed with sarcopenia, distal sensorimotor polyneuropathy, and Alzheimer’s disease. Low-grade chronic elevation of inflammatory markers was also revealed. We assumed that chronic low-grade inflammation with aging, also called “inflammaging,” contributed to the development of multiple comorbidities. After multidisciplinary treatment and comprehensive rehabilitation, he could ambulate again with minimal to moderate assistance. Various age-related disorders should be suspected when older patients present with chronic low-grade inflammation.