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Newly Diagnosed Sarcopenia and Alzheimer’s Disease in an Older Patient With Chronic Inflammation
A 78-year-old man presented with the aggravation of weakness in the lower extremities, gait disturbance, and cognitive impairment. He was diagnosed with sarcopenia, distal sensorimotor polyneuropathy, and Alzheimer’s disease. Low-grade chronic elevation of inflammatory markers was also revealed. We...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Geriatrics Society
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387604/ https://www.ncbi.nlm.nih.gov/pubmed/32743285 http://dx.doi.org/10.4235/agmr.19.0005 |
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author | Kim, Sun-Hyung Sin, Deok Su Lim, Jae-Young |
author_facet | Kim, Sun-Hyung Sin, Deok Su Lim, Jae-Young |
author_sort | Kim, Sun-Hyung |
collection | PubMed |
description | A 78-year-old man presented with the aggravation of weakness in the lower extremities, gait disturbance, and cognitive impairment. He was diagnosed with sarcopenia, distal sensorimotor polyneuropathy, and Alzheimer’s disease. Low-grade chronic elevation of inflammatory markers was also revealed. We assumed that chronic low-grade inflammation with aging, also called “inflammaging,” contributed to the development of multiple comorbidities. After multidisciplinary treatment and comprehensive rehabilitation, he could ambulate again with minimal to moderate assistance. Various age-related disorders should be suspected when older patients present with chronic low-grade inflammation. |
format | Online Article Text |
id | pubmed-7387604 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Korean Geriatrics Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-73876042020-07-30 Newly Diagnosed Sarcopenia and Alzheimer’s Disease in an Older Patient With Chronic Inflammation Kim, Sun-Hyung Sin, Deok Su Lim, Jae-Young Ann Geriatr Med Res Case Report A 78-year-old man presented with the aggravation of weakness in the lower extremities, gait disturbance, and cognitive impairment. He was diagnosed with sarcopenia, distal sensorimotor polyneuropathy, and Alzheimer’s disease. Low-grade chronic elevation of inflammatory markers was also revealed. We assumed that chronic low-grade inflammation with aging, also called “inflammaging,” contributed to the development of multiple comorbidities. After multidisciplinary treatment and comprehensive rehabilitation, he could ambulate again with minimal to moderate assistance. Various age-related disorders should be suspected when older patients present with chronic low-grade inflammation. Korean Geriatrics Society 2019-03 2019-03-31 /pmc/articles/PMC7387604/ /pubmed/32743285 http://dx.doi.org/10.4235/agmr.19.0005 Text en Copyright © 2019 by The Korean Geriatric Society This is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Kim, Sun-Hyung Sin, Deok Su Lim, Jae-Young Newly Diagnosed Sarcopenia and Alzheimer’s Disease in an Older Patient With Chronic Inflammation |
title | Newly Diagnosed Sarcopenia and Alzheimer’s Disease in an Older Patient With Chronic Inflammation |
title_full | Newly Diagnosed Sarcopenia and Alzheimer’s Disease in an Older Patient With Chronic Inflammation |
title_fullStr | Newly Diagnosed Sarcopenia and Alzheimer’s Disease in an Older Patient With Chronic Inflammation |
title_full_unstemmed | Newly Diagnosed Sarcopenia and Alzheimer’s Disease in an Older Patient With Chronic Inflammation |
title_short | Newly Diagnosed Sarcopenia and Alzheimer’s Disease in an Older Patient With Chronic Inflammation |
title_sort | newly diagnosed sarcopenia and alzheimer’s disease in an older patient with chronic inflammation |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387604/ https://www.ncbi.nlm.nih.gov/pubmed/32743285 http://dx.doi.org/10.4235/agmr.19.0005 |
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