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Newly Diagnosed Sarcopenia and Alzheimer’s Disease in an Older Patient With Chronic Inflammation

A 78-year-old man presented with the aggravation of weakness in the lower extremities, gait disturbance, and cognitive impairment. He was diagnosed with sarcopenia, distal sensorimotor polyneuropathy, and Alzheimer’s disease. Low-grade chronic elevation of inflammatory markers was also revealed. We...

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Autores principales: Kim, Sun-Hyung, Sin, Deok Su, Lim, Jae-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Geriatrics Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387604/
https://www.ncbi.nlm.nih.gov/pubmed/32743285
http://dx.doi.org/10.4235/agmr.19.0005
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author Kim, Sun-Hyung
Sin, Deok Su
Lim, Jae-Young
author_facet Kim, Sun-Hyung
Sin, Deok Su
Lim, Jae-Young
author_sort Kim, Sun-Hyung
collection PubMed
description A 78-year-old man presented with the aggravation of weakness in the lower extremities, gait disturbance, and cognitive impairment. He was diagnosed with sarcopenia, distal sensorimotor polyneuropathy, and Alzheimer’s disease. Low-grade chronic elevation of inflammatory markers was also revealed. We assumed that chronic low-grade inflammation with aging, also called “inflammaging,” contributed to the development of multiple comorbidities. After multidisciplinary treatment and comprehensive rehabilitation, he could ambulate again with minimal to moderate assistance. Various age-related disorders should be suspected when older patients present with chronic low-grade inflammation.
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spelling pubmed-73876042020-07-30 Newly Diagnosed Sarcopenia and Alzheimer’s Disease in an Older Patient With Chronic Inflammation Kim, Sun-Hyung Sin, Deok Su Lim, Jae-Young Ann Geriatr Med Res Case Report A 78-year-old man presented with the aggravation of weakness in the lower extremities, gait disturbance, and cognitive impairment. He was diagnosed with sarcopenia, distal sensorimotor polyneuropathy, and Alzheimer’s disease. Low-grade chronic elevation of inflammatory markers was also revealed. We assumed that chronic low-grade inflammation with aging, also called “inflammaging,” contributed to the development of multiple comorbidities. After multidisciplinary treatment and comprehensive rehabilitation, he could ambulate again with minimal to moderate assistance. Various age-related disorders should be suspected when older patients present with chronic low-grade inflammation. Korean Geriatrics Society 2019-03 2019-03-31 /pmc/articles/PMC7387604/ /pubmed/32743285 http://dx.doi.org/10.4235/agmr.19.0005 Text en Copyright © 2019 by The Korean Geriatric Society This is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Kim, Sun-Hyung
Sin, Deok Su
Lim, Jae-Young
Newly Diagnosed Sarcopenia and Alzheimer’s Disease in an Older Patient With Chronic Inflammation
title Newly Diagnosed Sarcopenia and Alzheimer’s Disease in an Older Patient With Chronic Inflammation
title_full Newly Diagnosed Sarcopenia and Alzheimer’s Disease in an Older Patient With Chronic Inflammation
title_fullStr Newly Diagnosed Sarcopenia and Alzheimer’s Disease in an Older Patient With Chronic Inflammation
title_full_unstemmed Newly Diagnosed Sarcopenia and Alzheimer’s Disease in an Older Patient With Chronic Inflammation
title_short Newly Diagnosed Sarcopenia and Alzheimer’s Disease in an Older Patient With Chronic Inflammation
title_sort newly diagnosed sarcopenia and alzheimer’s disease in an older patient with chronic inflammation
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387604/
https://www.ncbi.nlm.nih.gov/pubmed/32743285
http://dx.doi.org/10.4235/agmr.19.0005
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