CoenzymeQ10-Induced Activation of AMPK-YAP-OPA1 Pathway Alleviates Atherosclerosis by Improving Mitochondrial Function, Inhibiting Oxidative Stress and Promoting Energy Metabolism

Atherosclerosis (AS) is an excessive chronic inflammatory hyperplasia caused by the damage of vascular endothelial cell morphology and function. Changes in mitochondrial internal conformation and increase of reactive oxygen species (ROS) can lead to energy metabolism disorders in mitochondria, which...

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Detalles Bibliográficos
Autores principales: Xie, Tianqi, Wang, Changyuan, Jin, Yue, Meng, Qiang, Liu, Qi, Wu, Jingjing, Sun, Huijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387644/
https://www.ncbi.nlm.nih.gov/pubmed/32792941
http://dx.doi.org/10.3389/fphar.2020.01034

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