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DNA Methyltransferase 1 (DNMT1) Function Is Implicated in the Age-Related Loss of Cortical Interneurons

Increased life expectancy in modern society comes at the cost of age-associated disabilities and diseases. Aged brains not only show reduced excitability and plasticity, but also a decline in inhibition. Age-associated defects in inhibitory circuits likely contribute to cognitive decline and age-rel...

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Detalles Bibliográficos
Autores principales: Hahn, Anne, Pensold, Daniel, Bayer, Cathrin, Tittelmeier, Jessica, González-Bermúdez, Lourdes, Marx-Blümel, Lisa, Linde, Jenice, Groß, Jonas, Salinas-Riester, Gabriela, Lingner, Thomas, von Maltzahn, Julia, Spehr, Marc, Pieler, Tomas, Urbach, Anja, Zimmer-Bensch, Geraldine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387673/
https://www.ncbi.nlm.nih.gov/pubmed/32793592
http://dx.doi.org/10.3389/fcell.2020.00639