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Adaptive Potential of the Heme Oxygenase/Carbon Monoxide Pathway During Hypoxia

Heme oxygenase (HO) enzymes catalyze heme into biliverdin, releasing carbon monoxide (CO) and iron into circulation. These byproducts of heme degradation can have potent cytoprotective effects in the face of stressors such as hypoxia and ischemia-reperfusion events. The potential for exogenous use o...

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Detalles Bibliográficos
Autores principales: Tift, Michael S., Alves de Souza, Rodrigo W., Weber, Janick, Heinrich, Erica C., Villafuerte, Francisco C., Malhotra, Atul, Otterbein, Leo E., Simonson, Tatum S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387684/
https://www.ncbi.nlm.nih.gov/pubmed/32792988
http://dx.doi.org/10.3389/fphys.2020.00886

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