Epigenetic Input Dictates the Threshold of Targeting of the Integrin-Dependent Pathway in Non-small Cell Lung Cancer

We investigated the therapeutic potential of targeting integrin/FAK-dependent signaling, an adhesion receptor-mediated pathway that has been increasingly linked to non-small cell lung cancer (NSCLC) malignancy. Our analysis of the TCGA cohort showed that a subset of pro-tumorigenic integrins, includ...

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Detalles Bibliográficos
Autores principales: Zhang, Yang, Cheng, Kai, Xu, Bingwei, Shi, Junfeng, Qiang, Jun, Shi, Shujin, Yi, Yuanqin, Li, Hongxia, Jin, Tengchuan, Guo, Ruihua, Wu, Yadi, Liu, Zeyi, Wei, Xiaowei, Huang, Jian-An, Yang, Xiuwei H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387701/
https://www.ncbi.nlm.nih.gov/pubmed/32793596
http://dx.doi.org/10.3389/fcell.2020.00652

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