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Cancer Cell Metabolism Bolsters Immunotherapy Resistance by Promoting an Immunosuppressive Tumor Microenvironment
Immune checkpoint inhibitors (ICIs) targeting immune checkpoint proteins, such as CTLA-4 and PD-1/PD-L1, have demonstrated remarkable and durable clinical responses in various cancer types. However, a considerable number of patients receiving ICIs eventually experience a relapse due to diverse resis...
Autores principales: | Jiang, Zhou, Hsu, Jennifer L., Li, Yintao, Hortobagyi, Gabriel N., Hung, Mien-Chie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387712/ https://www.ncbi.nlm.nih.gov/pubmed/32775303 http://dx.doi.org/10.3389/fonc.2020.01197 |
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