Microbiota-derived butyrate limits the autoimmune response by promoting the differentiation of follicular regulatory T cells

BACKGROUND: Rheumatoid arthritis (RA) is a chronic debilitating autoimmune disorder with a high prevalence, especially in industrialized countries. Dysbiosis of the intestinal microbiota has been observed in RA patients. For instance, new-onset untreated RA (NORA) is associated with the underreprese...

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Detalles Bibliográficos
Autores principales: Takahashi, Daisuke, Hoshina, Naomi, Kabumoto, Yuma, Maeda, Yuichi, Suzuki, Akari, Tanabe, Hiyori, Isobe, Junya, Yamada, Takahiro, Muroi, Kisara, Yanagisawa, Yuto, Nakamura, Atsuo, Fujimura, Yumiko, Saeki, Aiko, Ueda, Mizuki, Matsumoto, Ryohtaroh, Asaoka, Hanako, Clarke, Julie M., Harada, Yohsuke, Umemoto, Eiji, Komatsu, Noriko, Okada, Takaharu, Takayanagi, Hiroshi, Takeda, Kiyoshi, Tomura, Michio, Hase, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387783/
https://www.ncbi.nlm.nih.gov/pubmed/32711255
http://dx.doi.org/10.1016/j.ebiom.2020.102913

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