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Polyphosphate Functions In Vivo as an Iron Chelator and Fenton Reaction Inhibitor
Maintaining cellular iron homeostasis is critical for organismal survival. Whereas iron depletion negatively affects the many metabolic pathways that depend on the activity of iron-containing enzymes, any excess of iron can cause the rapid formation of highly toxic reactive oxygen species (ROS) thro...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Microbiology
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387796/ https://www.ncbi.nlm.nih.gov/pubmed/32723918 http://dx.doi.org/10.1128/mBio.01017-20 |