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Design of a loading system for cyclic test on sutured organs

The design of loading systems to test biologic samples is often challenging, due to shape variability and non-conventional loading set-ups. In addition to this, large economic investments would not be justified since the loading set up is usually designed for one single or for a limited range of app...

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Autores principales: Pascoletti, Giulia, Pressanto, Maria Chiara, Putame, Giovanni, Terzini, Mara, Franceschini, Giordano, Zanetti, Elisabetta M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387823/
https://www.ncbi.nlm.nih.gov/pubmed/32742943
http://dx.doi.org/10.1016/j.mex.2020.100988
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author Pascoletti, Giulia
Pressanto, Maria Chiara
Putame, Giovanni
Terzini, Mara
Franceschini, Giordano
Zanetti, Elisabetta M.
author_facet Pascoletti, Giulia
Pressanto, Maria Chiara
Putame, Giovanni
Terzini, Mara
Franceschini, Giordano
Zanetti, Elisabetta M.
author_sort Pascoletti, Giulia
collection PubMed
description The design of loading systems to test biologic samples is often challenging, due to shape variability and non-conventional loading set-ups. In addition to this, large economic investments would not be justified since the loading set up is usually designed for one single or for a limited range of applications. The object of this work is the development of a loading set-up finalised to on-site testing of sutures whose main function is applying a localised tensile load. The main challenges of this design process can be so summarized: • Applying cyclic tensile loads on the suture wire, mimicking the physiologic condition where both suture anchorage points have a certain compliance; • Designing a loading system as versatile as possible, in order to be able to accommodate organs with different geometries and sizes; • Keeping low both the complexity and costs of realization. All these considerations and the design calculi are here reported in detail, discussing the novelty of the system, and its main advantages.
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spelling pubmed-73878232020-07-31 Design of a loading system for cyclic test on sutured organs Pascoletti, Giulia Pressanto, Maria Chiara Putame, Giovanni Terzini, Mara Franceschini, Giordano Zanetti, Elisabetta M. MethodsX Engineering The design of loading systems to test biologic samples is often challenging, due to shape variability and non-conventional loading set-ups. In addition to this, large economic investments would not be justified since the loading set up is usually designed for one single or for a limited range of applications. The object of this work is the development of a loading set-up finalised to on-site testing of sutures whose main function is applying a localised tensile load. The main challenges of this design process can be so summarized: • Applying cyclic tensile loads on the suture wire, mimicking the physiologic condition where both suture anchorage points have a certain compliance; • Designing a loading system as versatile as possible, in order to be able to accommodate organs with different geometries and sizes; • Keeping low both the complexity and costs of realization. All these considerations and the design calculi are here reported in detail, discussing the novelty of the system, and its main advantages. Elsevier 2020-07-08 /pmc/articles/PMC7387823/ /pubmed/32742943 http://dx.doi.org/10.1016/j.mex.2020.100988 Text en © 2020 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Engineering
Pascoletti, Giulia
Pressanto, Maria Chiara
Putame, Giovanni
Terzini, Mara
Franceschini, Giordano
Zanetti, Elisabetta M.
Design of a loading system for cyclic test on sutured organs
title Design of a loading system for cyclic test on sutured organs
title_full Design of a loading system for cyclic test on sutured organs
title_fullStr Design of a loading system for cyclic test on sutured organs
title_full_unstemmed Design of a loading system for cyclic test on sutured organs
title_short Design of a loading system for cyclic test on sutured organs
title_sort design of a loading system for cyclic test on sutured organs
topic Engineering
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387823/
https://www.ncbi.nlm.nih.gov/pubmed/32742943
http://dx.doi.org/10.1016/j.mex.2020.100988
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