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The Lebanese left ventricular assist device experience, a success story despite the odds

BACKGROUND AND AIM: Heart failure is still a leading cause of mortality and morbidity. Assist devices are reserved for advanced heart failure patients with no other therapeutic options. We aim in this paper to describe the characteristics and outcome of Lebanese left ventricular assist device (LVAD)...

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Autores principales: Hamdan, R., Fakih, S., Mohammad, M., Charif, F., Abdallah, H., Safa, S., Al Ali, F., Issa, M., Damen, B., el Zein, A., Younes, M., Rabah, A., Saab, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7388207/
https://www.ncbi.nlm.nih.gov/pubmed/32723392
http://dx.doi.org/10.1186/s13019-020-01235-7
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author Hamdan, R.
Fakih, S.
Mohammad, M.
Charif, F.
Abdallah, H.
Safa, S.
Al Ali, F.
Issa, M.
Damen, B.
el Zein, A.
Younes, M.
Rabah, A.
Saab, M.
author_facet Hamdan, R.
Fakih, S.
Mohammad, M.
Charif, F.
Abdallah, H.
Safa, S.
Al Ali, F.
Issa, M.
Damen, B.
el Zein, A.
Younes, M.
Rabah, A.
Saab, M.
author_sort Hamdan, R.
collection PubMed
description BACKGROUND AND AIM: Heart failure is still a leading cause of mortality and morbidity. Assist devices are reserved for advanced heart failure patients with no other therapeutic options. We aim in this paper to describe the characteristics and outcome of Lebanese left ventricular assist device (LVAD) patients. RESULTS: From 2010 till December 2019, 78 patients were implanted with assist devices at the Beirut cardiac Institute, 82 pumps were used. To the most recent follow up after 10 years, 26 patients died (34%). 24 patients of 35 (68%) survived more than 5 years. Seven patients only (9%) died during one month of surgery. One year mortality was 19% (15 patients). The leading cause of early mortality was infection, whereas cerebrovascular accidents CVA were the leading cause of late mortality. Pump thrombosis occurred in 12% of the cases. The most serious long term complication was haemorrhagic CVA. Only seven patients (9%) received heart transplantation, with a mean time on support prior to transplantation of 1303 ± 213 days. CONCLUSION: In this manuscript we reported the characteristics and outcome of the largest population of LVAD patients in Lebanon. The survival rate was 81% at one year. These findings were comparable to the international registries except for rates of heart transplantation. More efforts should be made to encourage organ donation in Lebanon.
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spelling pubmed-73882072020-07-30 The Lebanese left ventricular assist device experience, a success story despite the odds Hamdan, R. Fakih, S. Mohammad, M. Charif, F. Abdallah, H. Safa, S. Al Ali, F. Issa, M. Damen, B. el Zein, A. Younes, M. Rabah, A. Saab, M. J Cardiothorac Surg Research Article BACKGROUND AND AIM: Heart failure is still a leading cause of mortality and morbidity. Assist devices are reserved for advanced heart failure patients with no other therapeutic options. We aim in this paper to describe the characteristics and outcome of Lebanese left ventricular assist device (LVAD) patients. RESULTS: From 2010 till December 2019, 78 patients were implanted with assist devices at the Beirut cardiac Institute, 82 pumps were used. To the most recent follow up after 10 years, 26 patients died (34%). 24 patients of 35 (68%) survived more than 5 years. Seven patients only (9%) died during one month of surgery. One year mortality was 19% (15 patients). The leading cause of early mortality was infection, whereas cerebrovascular accidents CVA were the leading cause of late mortality. Pump thrombosis occurred in 12% of the cases. The most serious long term complication was haemorrhagic CVA. Only seven patients (9%) received heart transplantation, with a mean time on support prior to transplantation of 1303 ± 213 days. CONCLUSION: In this manuscript we reported the characteristics and outcome of the largest population of LVAD patients in Lebanon. The survival rate was 81% at one year. These findings were comparable to the international registries except for rates of heart transplantation. More efforts should be made to encourage organ donation in Lebanon. BioMed Central 2020-07-28 /pmc/articles/PMC7388207/ /pubmed/32723392 http://dx.doi.org/10.1186/s13019-020-01235-7 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Article
Hamdan, R.
Fakih, S.
Mohammad, M.
Charif, F.
Abdallah, H.
Safa, S.
Al Ali, F.
Issa, M.
Damen, B.
el Zein, A.
Younes, M.
Rabah, A.
Saab, M.
The Lebanese left ventricular assist device experience, a success story despite the odds
title The Lebanese left ventricular assist device experience, a success story despite the odds
title_full The Lebanese left ventricular assist device experience, a success story despite the odds
title_fullStr The Lebanese left ventricular assist device experience, a success story despite the odds
title_full_unstemmed The Lebanese left ventricular assist device experience, a success story despite the odds
title_short The Lebanese left ventricular assist device experience, a success story despite the odds
title_sort lebanese left ventricular assist device experience, a success story despite the odds
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7388207/
https://www.ncbi.nlm.nih.gov/pubmed/32723392
http://dx.doi.org/10.1186/s13019-020-01235-7
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