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Detection of leukemia gene fusions by targeted RNA-sequencing in routine diagnostics

BACKGROUND: We have evaluated an NGS-based method to detect recurrent gene fusions of diagnostic and prognostic importance in hematological malignancies. Our goal was to achieve a highly specific assay with a simple workflow, short turnaround time and low cost. METHOD: The assay uses a commercially...

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Detalles Bibliográficos
Autores principales:	Engvall, Marie, Cahill, Nicola, Jonsson, Britt-Inger, Höglund, Martin, Hallböök, Helene, Cavelier, Lucia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7388219/ https://www.ncbi.nlm.nih.gov/pubmed/32727569 http://dx.doi.org/10.1186/s12920-020-00739-4

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