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m(6)A methyltransferase METTL3 maintains colon cancer tumorigenicity by suppressing SOCS2 to promote cell proliferation

N(6)-methyladenosine (m(6)A) RNA modification maintained by N6-methyltransferases and demethylases is involved in multiple biological functions. Methyltransferase like 3 (METTL3) is a major N(6)-methyltransferase. However, the role of METTL3 and its installed m(6)A modification in colorectal tumorig...

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Detalles Bibliográficos
Autores principales: Xu, Jihao, Chen, Qikui, Tian, Kuangyi, Liang, Rongrong, Chen, Ting, Gong, Aiyu, Mathy, Nicholas W., Yu, Tao, Chen, Xianming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7388248/
https://www.ncbi.nlm.nih.gov/pubmed/32705223
http://dx.doi.org/10.3892/or.2020.7665

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