Cargando…
m(6)A methyltransferase METTL3 maintains colon cancer tumorigenicity by suppressing SOCS2 to promote cell proliferation
N(6)-methyladenosine (m(6)A) RNA modification maintained by N6-methyltransferases and demethylases is involved in multiple biological functions. Methyltransferase like 3 (METTL3) is a major N(6)-methyltransferase. However, the role of METTL3 and its installed m(6)A modification in colorectal tumorig...
Autores principales: | Xu, Jihao, Chen, Qikui, Tian, Kuangyi, Liang, Rongrong, Chen, Ting, Gong, Aiyu, Mathy, Nicholas W., Yu, Tao, Chen, Xianming |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7388248/ https://www.ncbi.nlm.nih.gov/pubmed/32705223 http://dx.doi.org/10.3892/or.2020.7665 |
Ejemplares similares
-
Faecalibacterium prausnitzii‐derived microbial anti‐inflammatory molecule regulates intestinal integrity in diabetes mellitus mice via modulating tight junction protein expression
por: Xu, Jihao, et al.
Publicado: (2019) -
Knockdown of m6A methyltransferase METTL3 in gastric cancer cells results in suppression of cell proliferation
por: Jiang, Li, et al.
Publicado: (2020) -
Emerging role of RNA methyltransferase METTL3 in gastrointestinal cancer
por: Wang, Qiang, et al.
Publicado: (2020) -
The Role of RNA Methyltransferase METTL3 in Normal and Malignant Hematopoiesis
por: Wu, Xia, et al.
Publicado: (2022) -
Solution structure of the RNA recognition domain of METTL3-METTL14 N(6)-methyladenosine methyltransferase
por: Huang, Jinbo, et al.
Publicado: (2018)