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The development of human immune system mice and their use to study tolerance and autoimmunity
Autoimmune diseases evolve from complex interactions between the immune system and self-antigens and involve several genetic attributes, environmental triggers and diverse cell types. Research using experimental mouse models has contributed key knowledge on the mechanisms that underlie these disease...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7388352/ https://www.ncbi.nlm.nih.gov/pubmed/32743507 http://dx.doi.org/10.1016/j.jtauto.2019.100021 |