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The development of human immune system mice and their use to study tolerance and autoimmunity

Autoimmune diseases evolve from complex interactions between the immune system and self-antigens and involve several genetic attributes, environmental triggers and diverse cell types. Research using experimental mouse models has contributed key knowledge on the mechanisms that underlie these disease...

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Detalles Bibliográficos
Autores principales: Alves da Costa, Thiago, Lang, Julie, Torres, Raul M., Pelanda, Roberta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7388352/
https://www.ncbi.nlm.nih.gov/pubmed/32743507
http://dx.doi.org/10.1016/j.jtauto.2019.100021