LncRNA FOXD3-AS1 promoted chemo-resistance of NSCLC cells via directly acting on miR-127-3p/MDM2 axis

BACKGROUND: This study aims to investigate the mechanism underlying the high level of long non-coding RNA FOXD3-AS1 in cisplatin-resistant NSCLC cells. METHODS: Cisplatin-resistant cells were generated from A549 cells. CCK-8 were used to evaluate cell proliferation. The FOXD3-AS1, miR-127-3p, MDM2 a...

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Detalles Bibliográficos
Autores principales: Zeng, Zhaolong, Zhao, Guofang, Zhu, Huangkai, Nie, Liangqin, He, Lifeng, Liu, Jiangtao, Li, Rui, Xiao, Shuai, Hua, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7388492/
https://www.ncbi.nlm.nih.gov/pubmed/32742197
http://dx.doi.org/10.1186/s12935-020-01402-9

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