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Phosphorylated Aβ peptides in human Down syndrome brain and different Alzheimer’s-like mouse models

The deposition of neurotoxic amyloid-β (Aβ) peptides in extracellular plaques in the brain parenchyma is one of the most prominent neuropathological features of Alzheimer’s disease (AD), and considered to be closely related to the pathogenesis of this disease. A number of recent studies demonstrate...

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Detalles Bibliográficos
Autores principales: Kumar, Sathish, Lemere, Cynthia A., Walter, Jochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7388542/
https://www.ncbi.nlm.nih.gov/pubmed/32727580
http://dx.doi.org/10.1186/s40478-020-00959-w