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Efficient detection of differentially methylated regions in the genome of patients with thoracic aortic dissection and association with MMP2 hypermethylation
DNA methylation is known to regulate the expression of numerous genes but its role in the pathogenesis of thoracic aortic dissection (TAD) has remained largely elusive. In the present study, the DNA methylome of patients with TAD was analyzed using a methylation microarray and bisulfite pyrosequenci...
Autores principales: | Li, Ni, Lin, Hangjuan, Zhou, Hua, Zheng, Dawei, Xu, Guodong, Shi, Huoshun, Zhu, Xiuying, Gao, Jianqing, Shao, Guofeng, Sun, Lebo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7388572/ https://www.ncbi.nlm.nih.gov/pubmed/32765660 http://dx.doi.org/10.3892/etm.2020.8753 |
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