Cargando…

Mechanistic investigations of antitumor activity of a Rhodamine B-oleanolic acid derivative bioconjugate

Mostrar otras versiones (1)

Cancer remains a major health problem worldwide due to its high mortality rate. New therapeutic options highlight the importance of discovering new compounds that target the tumor microenvironment, interrupt angiogenesis and act selectively. The present study assessed the antitumor effect and invest...

Descripción completa

Detalles Bibliográficos
Autores principales:	Macașoi, Ioana, Pavel, Ioana Zinuca, Moacă, Alina Elena, Avram, Ștefana, David, Vlad Laurențiu, Coricovac, Dorina, Mioc, Alexandra, Spandidos, Demetrios A., Tsatsakis, Aristidis, Șoica, Codruța, Dumitrașcu, Victor, Dehelean, Cristina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7388574/ https://www.ncbi.nlm.nih.gov/pubmed/32705265 http://dx.doi.org/10.3892/or.2020.7666

Ejemplares similares

Mechanistic investigations of antitumor activity of a Rhodamine B-oleanolic acid derivative bioconjugate
por: Macașoi, Ioana, et al.
Publicado: (2021)

Standardization of A375 human melanoma models on chicken embryo chorioallantoic membrane and Balb/c nude mice
por: Avram, Stefana, et al.
Publicado: (2017)

The Cytotoxic Effects of Betulin-Conjugated Gold Nanoparticles as Stable Formulations in Normal and Melanoma Cells
por: Mioc, Marius, et al.
Publicado: (2018)

Thermosensitive Betulinic Acid-Loaded Magnetoliposomes: A Promising Antitumor Potential for Highly Aggressive Human Breast Adenocarcinoma Cells Under Hyperthermic Conditions
por: Farcas, Claudia Geanina, et al.
Publicado: (2020)

Antibiotics: Conventional Therapy and Natural Compounds with Antibacterial Activity—A Pharmaco-Toxicological Screening
por: Pancu, Daniel Florin, et al.
Publicado: (2021)

Melissa officinalis L. Aqueous Extract Exerts Antioxidant and Antiangiogenic Effects and Improves Physiological Skin Parameters
por: Sipos, Simona, et al.
Publicado: (2021)

Lemon Balm Extracts Prevent Breast Cancer Progression In Vitro and In Ovo on Chorioallantoic Membrane Assay
por: Ghiulai, Roxana, et al.
Publicado: (2020)

Novel Synthesized N-Ethyl-Piperazinyl-Amides of C2-Substituted Oleanonic and Ursonic Acids Exhibit Cytotoxic Effects through Apoptotic Cell Death Regulation
por: Kazakova, Oxana, et al.
Publicado: (2021)

Effects of ursolic and oleanolic on SK-MEL-2 melanoma cells: In vitro and in vivo assays
por: Caunii, Angela, et al.
Publicado: (2017)

Design, synthesis and pharmaco-toxicological assessment of 5-mercapto-1,2,4-triazole derivatives with antibacterial and antiproliferative activity
por: Mioc, Marius, et al.
Publicado: (2017)

SARS-CoV-2: Repurposed Drugs and Novel Therapeutic Approaches—Insights into Chemical Structure—Biological Activity and Toxicological Screening
por: Dehelean, Cristina Adriana, et al.
Publicado: (2020)

The Synergistic Biologic Activity of Oleanolic and Ursolic Acids in Complex with Hydroxypropyl-γ-Cyclodextrin
por: Soica, Codruţa, et al.
Publicado: (2014)

3-Pyridinylidene Derivatives of Chemically Modified Lupane and Ursane Triterpenes as Promising Anticancer Agents by Targeting Apoptosis
por: Kazakova, Oxana, et al.
Publicado: (2021)

Biocompatible Colloidal Suspensions Based on Magnetic Iron Oxide Nanoparticles: Synthesis, Characterization and Toxicological Profile
por: Coricovac, Dorina-Elena, et al.
Publicado: (2017)

Rutin bioconjugates as potential nutraceutical prodrugs: An in vitro and in ovo toxicological screening
por: Dehelean, Cristina Adriana, et al.
Publicado: (2022)

Assessment of Betulinic Acid Cytotoxicity and Mitochondrial Metabolism Impairment in a Human Melanoma Cell Line
por: Coricovac, Dorina, et al.
Publicado: (2021)

Structural Investigation of Betulinic Acid Plasma Metabolites by Tandem Mass Spectrometry
por: Ghiulai, Roxana, et al.
Publicado: (2022)

Anticancer Potential of Betulonic Acid Derivatives
por: Lombrea, Adelina, et al.
Publicado: (2021)

Fe(3)O(4)@C Matrix with Tailorable Adsorption Capacities for Paracetamol and Acetylsalicylic Acid: Synthesis, Characterization, and Kinetic Modeling
por: Moacă, Elena-Alina, et al.
Publicado: (2019)

Design, Synthesis and Biological Activity Evaluation of S-Substituted 1H-5-Mercapto-1,2,4-Triazole Derivatives as Antiproliferative Agents in Colorectal Cancer
por: Mioc, Marius, et al.
Publicado: (2018)

Plant-Derived Anticancer Compounds as New Perspectives in Drug Discovery and Alternative Therapy
por: Dehelean, Cristina Adriana, et al.
Publicado: (2021)

Exposure to cadmium and copper triggers cytotoxic effects and epigenetic changes in human colorectal carcinoma HT-29 cells
por: Iftode, Andrada, et al.
Publicado: (2021)

Recent Advances Regarding the Phytochemical and Therapeutic Uses of Populus nigra L. Buds
por: Kis, Brigitta, et al.
Publicado: (2020)

A Recent Insight Regarding the Phytochemistry and Bioactivity of Origanum vulgare L. Essential Oil
por: Lombrea, Adelina, et al.
Publicado: (2020)

Novel Triterpenic Acid—Benzotriazole Esters Act as Pro-Apoptotic Antimelanoma Agents
por: Mioc, Marius, et al.
Publicado: (2022)

Phytochemical and Biological Screening of Oenothera biennis L. Hydroalcoholic Extract
por: Fecker, Ramona, et al.
Publicado: (2020)

Antimicrobial activity, in vitro anticancer effect (MCF-7 breast cancer cell line), antiangiogenic and immunomodulatory potentials of Populus nigra L. buds extract
por: Kis, Brigitta, et al.
Publicado: (2022)

Cannabidiol—from Plant to Human Body: A Promising Bioactive Molecule with Multi-Target Effects in Cancer
por: Kis, Brigitta, et al.
Publicado: (2019)

Tetracyclic and Pentacyclic Triterpenes with High Therapeutic Efficiency in Wound Healing Approaches
por: Ghiulai, Roxana, et al.
Publicado: (2020)

In Vitro Assessment of the Cytotoxic and Antiproliferative Profile of Natural Preparations Containing Bergamot, Orange and Clove Essential Oils
por: Alexa, Vlad Tiberiu, et al.
Publicado: (2022)

Controlled Synthesis and Characterization of Micrometric Single Crystalline Magnetite With Superparamagnetic Behavior and Cytocompatibility/Cytotoxicity Assessments
por: Farcas, Claudia Geanina, et al.
Publicado: (2020)

The Anti-Melanoma Effect of Betulinic Acid Functionalized Gold Nanoparticles: A Mechanistic In Vitro Approach
por: Ghiulai, Roxana, et al.
Publicado: (2022)

A Comprehensive Assessment of Apigenin as an Antiproliferative, Proapoptotic, Antiangiogenic and Immunomodulatory Phytocompound
por: Ghițu, Alexandra, et al.
Publicado: (2019)

Betulinic Acid in Complex with a Gamma-Cyclodextrin Derivative Decreases Proliferation and in Vivo Tumor Development of Non-Metastatic and Metastatic B164A5 Cells
por: Soica, Codruta, et al.
Publicado: (2014)

Ethinylestradiol and Levonorgestrel as Active Agents in Normal Skin, and Pathological Conditions Induced by UVB Exposure: In Vitro and In Ovo Assessments
por: Coricovac, Dorina, et al.
Publicado: (2018)

Melanin and Melanin-Functionalized Nanoparticles as Promising Tools in Cancer Research—A Review
por: Marcovici, Iasmina, et al.
Publicado: (2022)

Classification of cancer cell lines using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and statistical analysis
por: Serafim, Vlad, et al.
Publicado: (2017)

Assessment of the Antiangiogenic and Anti-Inflammatory Properties of a Maslinic Acid Derivative and its Potentiation using Zinc Chloride
por: Pavel, Ioana Zinuca, et al.
Publicado: (2019)

Cocrystal Formation of Betulinic Acid and Ascorbic Acid: Synthesis, Physico-Chemical Assessment, Antioxidant, and Antiproliferative Activity
por: Nicolov, Mirela, et al.
Publicado: (2019)

A Comparative Study of Melissa officinalis Leaves and Stems Ethanolic Extracts in terms of Antioxidant, Cytotoxic, and Antiproliferative Potential
por: Moacă, Elena-Alina, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_ec660njfuiu223csqq1n7gh7oj