Early Insights From Clinical Trials of Typhoid Conjugate Vaccine

Clinical trials of typhoid conjugate vaccine (TCV) are ongoing in 4 countries. Early data confirm safety, tolerability, and immunogenicity of typhoid conjugate vaccine, and early efficacy results are promising. These data support World Health Organization recommendations and planned country introduc...

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Detalles Bibliográficos
Autores principales: Neuzil, Kathleen M, Basnyat, Buddha, Clemens, John D, Gordon, Melita A, Patel, Priyanka D, Pollard, Andrew J, Shakya, Mila, Qadri, Firdausi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Supplement Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7388715/
https://www.ncbi.nlm.nih.gov/pubmed/32725230
http://dx.doi.org/10.1093/cid/ciaa370
Descripción
Sumario:Clinical trials of typhoid conjugate vaccine (TCV) are ongoing in 4 countries. Early data confirm safety, tolerability, and immunogenicity of typhoid conjugate vaccine, and early efficacy results are promising. These data support World Health Organization recommendations and planned country introductions. Forthcoming trial data will continue to inform programmatic use of typhoid conjugate vaccine.

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