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The Mechanism of Ferroptosis and Applications in Tumor Treatment

Iron-dependent ferroptosis is a new form of cell death in recent years, which is driven by lipid peroxidation. The lethal lipid accumulation caused by glutathione depletion or inactivation of glutathione peroxidase 4 (GPX4) is characteristic of the ferroptosis process. In recent years, with the in-d...

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Detalles Bibliográficos
Autores principales: Lin, Xinyue, Ping, Jieyi, Wen, Yi, Wu, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7388725/
https://www.ncbi.nlm.nih.gov/pubmed/32774303
http://dx.doi.org/10.3389/fphar.2020.01061