Emerging Therapies in Thoracic Malignancies—Immunotherapy, Targeted Therapy, and T-Cell Therapy in Non–Small Cell Lung Cancer

Immunotherapy, targeted therapy, and adoptive T-cell therapy have been revolutionary advancements in cancer research. Some of these therapies have become the standard of care for lung cancer and replaced older treatment algorithms; some continue to be studied in clinical trials. This article discuss...

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Detalles Bibliográficos
Autores principales: Sepesi, Boris, Cascone, Tina, Chun, Stephen G., Altan, Mehmet, Le, Xiuning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7388816/
https://www.ncbi.nlm.nih.gov/pubmed/32883458
http://dx.doi.org/10.1016/j.soc.2020.06.009
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author Sepesi, Boris
Cascone, Tina
Chun, Stephen G.
Altan, Mehmet
Le, Xiuning
author_facet Sepesi, Boris
Cascone, Tina
Chun, Stephen G.
Altan, Mehmet
Le, Xiuning
author_sort Sepesi, Boris
collection PubMed
description Immunotherapy, targeted therapy, and adoptive T-cell therapy have been revolutionary advancements in cancer research. Some of these therapies have become the standard of care for lung cancer and replaced older treatment algorithms; some continue to be studied in clinical trials. This article discusses the current state of novel treatment options for non–small cell lung cancer patients with metastatic and locoregional disease, with focus on immunotherapy, targeted therapy, and adoptive T-cell therapy.
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spelling pubmed-73888162020-07-30 Emerging Therapies in Thoracic Malignancies—Immunotherapy, Targeted Therapy, and T-Cell Therapy in Non–Small Cell Lung Cancer Sepesi, Boris Cascone, Tina Chun, Stephen G. Altan, Mehmet Le, Xiuning Surg Oncol Clin N Am Article Immunotherapy, targeted therapy, and adoptive T-cell therapy have been revolutionary advancements in cancer research. Some of these therapies have become the standard of care for lung cancer and replaced older treatment algorithms; some continue to be studied in clinical trials. This article discusses the current state of novel treatment options for non–small cell lung cancer patients with metastatic and locoregional disease, with focus on immunotherapy, targeted therapy, and adoptive T-cell therapy. Elsevier Inc. 2020-10 2020-07-29 /pmc/articles/PMC7388816/ /pubmed/32883458 http://dx.doi.org/10.1016/j.soc.2020.06.009 Text en © 2020 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Sepesi, Boris
Cascone, Tina
Chun, Stephen G.
Altan, Mehmet
Le, Xiuning
Emerging Therapies in Thoracic Malignancies—Immunotherapy, Targeted Therapy, and T-Cell Therapy in Non–Small Cell Lung Cancer
title Emerging Therapies in Thoracic Malignancies—Immunotherapy, Targeted Therapy, and T-Cell Therapy in Non–Small Cell Lung Cancer
title_full Emerging Therapies in Thoracic Malignancies—Immunotherapy, Targeted Therapy, and T-Cell Therapy in Non–Small Cell Lung Cancer
title_fullStr Emerging Therapies in Thoracic Malignancies—Immunotherapy, Targeted Therapy, and T-Cell Therapy in Non–Small Cell Lung Cancer
title_full_unstemmed Emerging Therapies in Thoracic Malignancies—Immunotherapy, Targeted Therapy, and T-Cell Therapy in Non–Small Cell Lung Cancer
title_short Emerging Therapies in Thoracic Malignancies—Immunotherapy, Targeted Therapy, and T-Cell Therapy in Non–Small Cell Lung Cancer
title_sort emerging therapies in thoracic malignancies—immunotherapy, targeted therapy, and t-cell therapy in non–small cell lung cancer
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7388816/
https://www.ncbi.nlm.nih.gov/pubmed/32883458
http://dx.doi.org/10.1016/j.soc.2020.06.009
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