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Identification and validation of the mode of action of the chalcone anti-mycobacterial compounds

OBJECTIVES: The search for new TB drugs has become one of the great challenges for modern medicinal chemistry. An improvement in the outcomes of TB chemotherapy can be achieved by the development of new, shorter, cheap, safe and effective anti-TB regimens. METHODS: Chalcones (1a-1o) were synthesized...

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Detalles Bibliográficos
Autores principales:	Anagani, B., Singh, J., Bassin, J.P., Besra, G.S., Benham, C., Reddy, T.R.K., Cox, J.A.G., Goyal, M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7388970/ https://www.ncbi.nlm.nih.gov/pubmed/32743153 http://dx.doi.org/10.1016/j.tcsw.2020.100041

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