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Different effects of constitutive and induced microbiota modulation on microglia in a mouse model of Alzheimer’s disease

It was recently revealed that gut microbiota promote amyloid-beta (Aβ) burden in mouse models of Alzheimer’s disease (AD). However, the underlying mechanisms when using either germ-free (GF) housing conditions or treatments with antibiotics (ABX) remained unknown. In this study, we show that GF and...

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Detalles Bibliográficos
Autores principales:	Mezö, Charlotte, Dokalis, Nikolaos, Mossad, Omar, Staszewski, Ori, Neuber, Jana, Yilmaz, Bahtiyar, Schnepf, Daniel, de Agüero, Mercedes Gomez, Ganal-Vonarburg, Stephanie C., Macpherson, Andrew J., Meyer-Luehmann, Melanie, Staeheli, Peter, Blank, Thomas, Prinz, Marco, Erny, Daniel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7389451/ https://www.ncbi.nlm.nih.gov/pubmed/32727612 http://dx.doi.org/10.1186/s40478-020-00988-5

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