Safety and tolerability evaluation after repeated intravitreal injections of a humanized anti-VEGF-A monoclonal antibody (PRO-169) versus ranibizumab in New Zealand white rabbits

BACKGROUND: To evaluate the retinal toxicity after repeated intravitreal injections of a humanized anti-VEGF-A monoclonal antibody (PRO-169) versus ranibizumab in New Zealand white (NZW) rabbit eyes. METHODS: NZW rabbits were injected intravitreally with PRO-169 (n = 12), 1.25 mg/0.05 ml or ranibizu...

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Detalles Bibliográficos
Autores principales: Baiza-Durán, Leopoldo, Sánchez-Ríos, Alejandra, González-Barón, Joel, Olvera-Montaño, Oscar, Correa-Gallegos, Elba, Navarro-Sánchez, Andrea, Muñoz-Villegas, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7389522/
https://www.ncbi.nlm.nih.gov/pubmed/32742719
http://dx.doi.org/10.1186/s40942-020-00235-y

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