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Comparison of various risk scores for the prognosis of hemorrhagic upper gastrointestinal mucosal disorder

BACKGROUND: Various risk scores have been proposed that are useful for the management of upper gastrointestinal bleeding (UGIB), which is an important disease in emergency medicine. Few studies have examined the usefulness of Charlson Comorbidity index (CCI) in this disease, which evaluates the pati...

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Autores principales: Kita, Shinya, Shirai, Yasuyuki, Yoshida, Tomoharu, Shiraishi, Kei, Nakamura, Ayako, Kawano, Michitaka, Kinoshita, Yoshihiro, Noguchi, Tatsuya, Ito, Syunsuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7390105/
https://www.ncbi.nlm.nih.gov/pubmed/32727347
http://dx.doi.org/10.1186/s12245-020-00293-x
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author Kita, Shinya
Shirai, Yasuyuki
Yoshida, Tomoharu
Shiraishi, Kei
Nakamura, Ayako
Kawano, Michitaka
Kinoshita, Yoshihiro
Noguchi, Tatsuya
Ito, Syunsuke
author_facet Kita, Shinya
Shirai, Yasuyuki
Yoshida, Tomoharu
Shiraishi, Kei
Nakamura, Ayako
Kawano, Michitaka
Kinoshita, Yoshihiro
Noguchi, Tatsuya
Ito, Syunsuke
author_sort Kita, Shinya
collection PubMed
description BACKGROUND: Various risk scores have been proposed that are useful for the management of upper gastrointestinal bleeding (UGIB), which is an important disease in emergency medicine. Few studies have examined the usefulness of Charlson Comorbidity index (CCI) in this disease, which evaluates the patient’s general condition by scoring the patient’s underlying disease. There have been no studies investigating the efficacy of CCI compared to other risk scores in the management of UGIB requiring endoscopic hemostasis. METHODS: In addition to the Glasgow-Blatchford score, AIMS65 score, and Rockall score, we investigated the efficacy of the outcome prediction obtained by the original CCI and the updated CCI, scored only with respect to the underlying disease. We also examined the cutoff value when using the risk score. This retrospective study included 265 patients with hemorrhagic upper gastrointestinal mucosal lesions who underwent emergency endoscopic hemostasis during a 6-year period between 2011 and 2016 in our hospital. RESULTS: The updated CCI and AIMS65 score correlated with prognosis in multivariate analysis (p = 0.002 and p = 0.003, respectively). In clinical practice, the prognosis might be worse if both updated CCI and AIMS65 score were 3 point or more. CONCLUSION: In addition to the AIMS65 score, the updated CCI can be a useful tool for managing upper gastrointestinal mucosal disorder bleeding that requires endoscopic hemostasis.
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spelling pubmed-73901052020-07-31 Comparison of various risk scores for the prognosis of hemorrhagic upper gastrointestinal mucosal disorder Kita, Shinya Shirai, Yasuyuki Yoshida, Tomoharu Shiraishi, Kei Nakamura, Ayako Kawano, Michitaka Kinoshita, Yoshihiro Noguchi, Tatsuya Ito, Syunsuke Int J Emerg Med Original Research BACKGROUND: Various risk scores have been proposed that are useful for the management of upper gastrointestinal bleeding (UGIB), which is an important disease in emergency medicine. Few studies have examined the usefulness of Charlson Comorbidity index (CCI) in this disease, which evaluates the patient’s general condition by scoring the patient’s underlying disease. There have been no studies investigating the efficacy of CCI compared to other risk scores in the management of UGIB requiring endoscopic hemostasis. METHODS: In addition to the Glasgow-Blatchford score, AIMS65 score, and Rockall score, we investigated the efficacy of the outcome prediction obtained by the original CCI and the updated CCI, scored only with respect to the underlying disease. We also examined the cutoff value when using the risk score. This retrospective study included 265 patients with hemorrhagic upper gastrointestinal mucosal lesions who underwent emergency endoscopic hemostasis during a 6-year period between 2011 and 2016 in our hospital. RESULTS: The updated CCI and AIMS65 score correlated with prognosis in multivariate analysis (p = 0.002 and p = 0.003, respectively). In clinical practice, the prognosis might be worse if both updated CCI and AIMS65 score were 3 point or more. CONCLUSION: In addition to the AIMS65 score, the updated CCI can be a useful tool for managing upper gastrointestinal mucosal disorder bleeding that requires endoscopic hemostasis. Springer Berlin Heidelberg 2020-07-29 /pmc/articles/PMC7390105/ /pubmed/32727347 http://dx.doi.org/10.1186/s12245-020-00293-x Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Original Research
Kita, Shinya
Shirai, Yasuyuki
Yoshida, Tomoharu
Shiraishi, Kei
Nakamura, Ayako
Kawano, Michitaka
Kinoshita, Yoshihiro
Noguchi, Tatsuya
Ito, Syunsuke
Comparison of various risk scores for the prognosis of hemorrhagic upper gastrointestinal mucosal disorder
title Comparison of various risk scores for the prognosis of hemorrhagic upper gastrointestinal mucosal disorder
title_full Comparison of various risk scores for the prognosis of hemorrhagic upper gastrointestinal mucosal disorder
title_fullStr Comparison of various risk scores for the prognosis of hemorrhagic upper gastrointestinal mucosal disorder
title_full_unstemmed Comparison of various risk scores for the prognosis of hemorrhagic upper gastrointestinal mucosal disorder
title_short Comparison of various risk scores for the prognosis of hemorrhagic upper gastrointestinal mucosal disorder
title_sort comparison of various risk scores for the prognosis of hemorrhagic upper gastrointestinal mucosal disorder
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7390105/
https://www.ncbi.nlm.nih.gov/pubmed/32727347
http://dx.doi.org/10.1186/s12245-020-00293-x
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