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Correlation between the HIF-1α/Notch signaling pathway and Modic changes in nucleus pulposus cells isolated from patients with low back pain

BACKGROUND: The HIF-1α/Notch signaling pathway regulates cell proliferation, apoptosis, and metabolism in the intervertebral discs (IVDs) and is implicated in disc degeneration. The nucleus pulposus (NP) is an important structure adjacent to the IVDs. However, the role of the HIF-1α/Notch signaling...

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Detalles Bibliográficos
Autores principales:	Xiong, Zekang, Ding, Jun, Zhou, Jinge, Yao, Sheng, Zheng, Jin, Guo, Xiaodong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7390108/ https://www.ncbi.nlm.nih.gov/pubmed/32723315 http://dx.doi.org/10.1186/s12891-020-03505-w

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