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An Optimized Protocol for Human Direct Cardiac Reprogramming
Direct cardiac reprogramming, the conversion of fibroblasts into cardiomyocyte-like cells (iCMs), is an attractive approach to heal the injured heart. Here we present a new approach to human cardiac reprogramming that utilizes a polycistronic three-factor reprogramming cocktail and one microRNA. Our...
Autores principales: | Garbutt, Tiffany A., Zhou, Yang, Keepers, Benjamin, Liu, Jiandong, Qian, Li |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7390466/ https://www.ncbi.nlm.nih.gov/pubmed/32728671 http://dx.doi.org/10.1016/j.xpro.2019.100010 |
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