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Effects of Heat Shock Protein 90 Inhibition In the Lungs
Inhibition of Hsp90 is associated with anti-inflammatory effects. We employed human lung microvascular endothelial cells to investigate the effects of the Hsp90 inhibitors 17-AAG, AUY-922 and 17-DMAG in the unfolded protein response (UPR) and viability of lung cells. Our observations indicate that m...
Autores principales: | Uddin, Mohammad A., Kubra, Khadeja-Tul, Sonju, Jafrin Jobayer, Akhter, Mohammad S., Seetharama, Jois, Barabutis, Nektarios |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7390472/ https://www.ncbi.nlm.nih.gov/pubmed/32728665 http://dx.doi.org/10.1016/j.medidd.2020.100046 |
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