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Enantioselective radical C–H amination for the synthesis of β-amino alcohols
Asymmetric, radical C–H functionalizations are rare, yet powerful tools for solving modern synthetic challenges. Specifically, the enantio- and regio-selective C–H amination of alcohols to access medicinally valuable, chiral β-amino alcohols remains elusive. To solve this challenge, a radical relay...
Autores principales: | Nakafuku, Kohki M., Zhang, Zuxiao, Wappes, Ethan A., Stateman, Leah M., Chen, Andrew D., Nagib, David A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7390680/ https://www.ncbi.nlm.nih.gov/pubmed/32572164 http://dx.doi.org/10.1038/s41557-020-0482-8 |
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