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Enantioselective radical C–H amination for the synthesis of β-amino alcohols

Asymmetric, radical C–H functionalizations are rare, yet powerful tools for solving modern synthetic challenges. Specifically, the enantio- and regio-selective C–H amination of alcohols to access medicinally valuable, chiral β-amino alcohols remains elusive. To solve this challenge, a radical relay...

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Detalles Bibliográficos
Autores principales: Nakafuku, Kohki M., Zhang, Zuxiao, Wappes, Ethan A., Stateman, Leah M., Chen, Andrew D., Nagib, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7390680/
https://www.ncbi.nlm.nih.gov/pubmed/32572164
http://dx.doi.org/10.1038/s41557-020-0482-8

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