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Dentists' knowledge about medication-related osteonecrosis of the jaw and its management

OBJECTIVES: To assess the knowledge of dentists regarding medication-related osteonecrosis of the jaw (MRONJ). METHODS: In this cross-sectional study, 74 dentists from governmental hospitals in Riyadh (Dental University Hospital in King Saud University, Military Hospital, National Guard Hospital), J...

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Autores principales: Al-Eid, R., Alduwayan, T., Bin Khuthaylah, M., Al Shemali, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7390761/
https://www.ncbi.nlm.nih.gov/pubmed/32760820
http://dx.doi.org/10.1016/j.heliyon.2020.e04321
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author Al-Eid, R.
Alduwayan, T.
Bin Khuthaylah, M.
Al Shemali, M.
author_facet Al-Eid, R.
Alduwayan, T.
Bin Khuthaylah, M.
Al Shemali, M.
author_sort Al-Eid, R.
collection PubMed
description OBJECTIVES: To assess the knowledge of dentists regarding medication-related osteonecrosis of the jaw (MRONJ). METHODS: In this cross-sectional study, 74 dentists from governmental hospitals in Riyadh (Dental University Hospital in King Saud University, Military Hospital, National Guard Hospital), Jeddah (King Abdulaziz University Hospital, Ministry of Health Hospital), and the Eastern region of Saudi Arabia (Ministry of Health Hospitals in Dammam and Al-Ahsa) completed a two-part questionnaire. The first part gathered demographic data, such as sex and specialty. The second part included questions about bisphosphonate drugs and their indications; the identification of patients at risk of MRONJ; other medications associated with jaw necrosis; as well as the definition of MRONJ and its clinical features, risk factors, and preventive methods. RESULTS: Of the participating dentists, 60.8% knew about MRONJ, but only 35.1% were able to define it correctly. Most (79.7%) had never encountered MRONJ patients. Only 18.9% knew of the relationship between the risk of MRONJ in osteoporotic patients and long-term (>4 years) use of oral bisphosphonates or intravenous zoledronate, while 68.9% were unaware, and others answered incorrectly. Most participants did not know of MRONJ-predisposing medications, and 59.5% cited radiotherapy as the cause. Most participants identified dentoalveolar surgery as a major local factor, and the mandible as a common anatomic location. CONCLUSION: Dentists at the surveyed institutions had poor knowledge of MRONJ, although their knowledge of preventive measures was good. There is an urgent need for the optimization of educational programs pertaining to MRONJ, and its related dental management considerations. CLINICAL SIGNIFICANCE: Dentists in the surveyed institutions in Kingdom of Saudi Arabia have poor knowledge of MRONJ management; thus, greater effort should be taken to educate undergraduate and postgraduate students regarding this pathology.
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spelling pubmed-73907612020-08-04 Dentists' knowledge about medication-related osteonecrosis of the jaw and its management Al-Eid, R. Alduwayan, T. Bin Khuthaylah, M. Al Shemali, M. Heliyon Article OBJECTIVES: To assess the knowledge of dentists regarding medication-related osteonecrosis of the jaw (MRONJ). METHODS: In this cross-sectional study, 74 dentists from governmental hospitals in Riyadh (Dental University Hospital in King Saud University, Military Hospital, National Guard Hospital), Jeddah (King Abdulaziz University Hospital, Ministry of Health Hospital), and the Eastern region of Saudi Arabia (Ministry of Health Hospitals in Dammam and Al-Ahsa) completed a two-part questionnaire. The first part gathered demographic data, such as sex and specialty. The second part included questions about bisphosphonate drugs and their indications; the identification of patients at risk of MRONJ; other medications associated with jaw necrosis; as well as the definition of MRONJ and its clinical features, risk factors, and preventive methods. RESULTS: Of the participating dentists, 60.8% knew about MRONJ, but only 35.1% were able to define it correctly. Most (79.7%) had never encountered MRONJ patients. Only 18.9% knew of the relationship between the risk of MRONJ in osteoporotic patients and long-term (>4 years) use of oral bisphosphonates or intravenous zoledronate, while 68.9% were unaware, and others answered incorrectly. Most participants did not know of MRONJ-predisposing medications, and 59.5% cited radiotherapy as the cause. Most participants identified dentoalveolar surgery as a major local factor, and the mandible as a common anatomic location. CONCLUSION: Dentists at the surveyed institutions had poor knowledge of MRONJ, although their knowledge of preventive measures was good. There is an urgent need for the optimization of educational programs pertaining to MRONJ, and its related dental management considerations. CLINICAL SIGNIFICANCE: Dentists in the surveyed institutions in Kingdom of Saudi Arabia have poor knowledge of MRONJ management; thus, greater effort should be taken to educate undergraduate and postgraduate students regarding this pathology. Elsevier 2020-07-27 /pmc/articles/PMC7390761/ /pubmed/32760820 http://dx.doi.org/10.1016/j.heliyon.2020.e04321 Text en © 2020 The Authors. Published by Elsevier Ltd. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Al-Eid, R.
Alduwayan, T.
Bin Khuthaylah, M.
Al Shemali, M.
Dentists' knowledge about medication-related osteonecrosis of the jaw and its management
title Dentists' knowledge about medication-related osteonecrosis of the jaw and its management
title_full Dentists' knowledge about medication-related osteonecrosis of the jaw and its management
title_fullStr Dentists' knowledge about medication-related osteonecrosis of the jaw and its management
title_full_unstemmed Dentists' knowledge about medication-related osteonecrosis of the jaw and its management
title_short Dentists' knowledge about medication-related osteonecrosis of the jaw and its management
title_sort dentists' knowledge about medication-related osteonecrosis of the jaw and its management
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7390761/
https://www.ncbi.nlm.nih.gov/pubmed/32760820
http://dx.doi.org/10.1016/j.heliyon.2020.e04321
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