Physical stability and release properties of lumefantrine amorphous solid dispersion granules prepared by a simple solvent evaporation approach

Amorphous solid dispersions (ASDs) of lumefantrine, which has low aqueous solubility, have been shown to improve bioavailability relative to crystalline formulations. Herein, the crystallization tendency and release properties of a variety of lumefantrine ASD granules, formed on a blend of microcrys...

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Detalles Bibliográficos
Autores principales: Trasi, Niraj S., Bhujbal, Sonal V., Zemlyanov, Dmitry Y., Zhou, Qi (Tony), Taylor, Lynne S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7390794/
https://www.ncbi.nlm.nih.gov/pubmed/32760909
http://dx.doi.org/10.1016/j.ijpx.2020.100052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7390794/
https://www.ncbi.nlm.nih.gov/pubmed/32760909
http://dx.doi.org/10.1016/j.ijpx.2020.100052

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