COVID-19 Infection and High Intracoronary Thrombus Burden

Coronavirus 2019 (COVID-19) is an acute respiratory disease that has rapidly spread around the world and been declared a global pandemic by the World Health Organization. Emerging evidence demonstrates a strong association with a pro-thrombotic state and we present the first patient admitted with CO...

Descripción completa

Detalles Bibliográficos
Autores principales: Kirresh, Ali, Coghlan, Gerry, Candilio, Luciano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7390795/
https://www.ncbi.nlm.nih.gov/pubmed/32967797
http://dx.doi.org/10.1016/j.carrev.2020.07.032
_version_ 1783564515464445952
author Kirresh, Ali
Coghlan, Gerry
Candilio, Luciano
author_facet Kirresh, Ali
Coghlan, Gerry
Candilio, Luciano
author_sort Kirresh, Ali
collection PubMed
description Coronavirus 2019 (COVID-19) is an acute respiratory disease that has rapidly spread around the world and been declared a global pandemic by the World Health Organization. Emerging evidence demonstrates a strong association with a pro-thrombotic state and we present the first patient admitted with COVID-19 and an inferior ST-segment elevation myocardial infarction (STEMI) with evidence of high intracoronary thrombus burden. We review the mechanism of the high thrombus burden, which may be driven by the significant cytokine storm, endothelial dysfunction, increase risk of coronary plaque rupture and hypercoagulability.
format Online
Article
Text
id pubmed-7390795
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Elsevier Inc.
record_format MEDLINE/PubMed
spelling pubmed-73907952020-07-30 COVID-19 Infection and High Intracoronary Thrombus Burden Kirresh, Ali Coghlan, Gerry Candilio, Luciano Cardiovasc Revasc Med Review Coronavirus 2019 (COVID-19) is an acute respiratory disease that has rapidly spread around the world and been declared a global pandemic by the World Health Organization. Emerging evidence demonstrates a strong association with a pro-thrombotic state and we present the first patient admitted with COVID-19 and an inferior ST-segment elevation myocardial infarction (STEMI) with evidence of high intracoronary thrombus burden. We review the mechanism of the high thrombus burden, which may be driven by the significant cytokine storm, endothelial dysfunction, increase risk of coronary plaque rupture and hypercoagulability. Elsevier Inc. 2021-07 2020-07-30 /pmc/articles/PMC7390795/ /pubmed/32967797 http://dx.doi.org/10.1016/j.carrev.2020.07.032 Text en © 2020 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Review
Kirresh, Ali
Coghlan, Gerry
Candilio, Luciano
COVID-19 Infection and High Intracoronary Thrombus Burden
title COVID-19 Infection and High Intracoronary Thrombus Burden
title_full COVID-19 Infection and High Intracoronary Thrombus Burden
title_fullStr COVID-19 Infection and High Intracoronary Thrombus Burden
title_full_unstemmed COVID-19 Infection and High Intracoronary Thrombus Burden
title_short COVID-19 Infection and High Intracoronary Thrombus Burden
title_sort covid-19 infection and high intracoronary thrombus burden
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7390795/
https://www.ncbi.nlm.nih.gov/pubmed/32967797
http://dx.doi.org/10.1016/j.carrev.2020.07.032
work_keys_str_mv AT kirreshali covid19infectionandhighintracoronarythrombusburden
AT coghlangerry covid19infectionandhighintracoronarythrombusburden
AT candilioluciano covid19infectionandhighintracoronarythrombusburden

Ejemplares similares