Cargando…
The incidence and mortality trends of bone lymphoma in the United States: An analysis of the Surveillance, Epidemiology, and End Results database
BACKGROUND: In recent years, studies on bone lymphoma and its histologic types have reached a mature stage. However, reports on the incidence and incidence-based mortality trends of bone lymphoma are scanty. METHODS: Patients with bone lymphoma in the U.S. were selected from Surveillance, Epidemiolo...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7390813/ https://www.ncbi.nlm.nih.gov/pubmed/32760645 http://dx.doi.org/10.1016/j.jbo.2020.100306 |
_version_ | 1783564519198425088 |
---|---|
author | Xu, Daoliang Wang, Ben Chen, Lijie Zhang, Huawei Wang, Xiangyang Chen, Jiaoxiang |
author_facet | Xu, Daoliang Wang, Ben Chen, Lijie Zhang, Huawei Wang, Xiangyang Chen, Jiaoxiang |
author_sort | Xu, Daoliang |
collection | PubMed |
description | BACKGROUND: In recent years, studies on bone lymphoma and its histologic types have reached a mature stage. However, reports on the incidence and incidence-based mortality trends of bone lymphoma are scanty. METHODS: Patients with bone lymphoma in the U.S. were selected from Surveillance, Epidemiology, and End Results (SEER) database (1975–2016), and categorized based on age, sex, race, tumor location, SEER Historic Stage A and histologic type. Data on the incidence (1975–2016) and incidence-based mortality (1985–2016) were directly obtained from the SEER program. Annual percentage change (APC) and 95% confidence intervals (CIs) were calculated using the joinpoint regression analysis program. RESULTS: Overall, 13,058 bone lymphoma cases diagnosed in resident patients of the U.S. were included in incidence analysis between 1975 and 2016 as follows: 6080 cases in 1975–1999, 3796 cases in 2000–2009, and 3182 cases in 2010–2016. Of these cases, 6888 died of bone lymphoma between 1985 and 2016. The overall incidence rates dramatically increased from 0.89 per 100,000 person-years in 1975 to 1.36 per 100,000 person-years in 2016. Incidence trend sharply increased from 1975 to 2009, and then stabilized between 2009 and 2016. Overall incidence-based mortality trends sharply increased from 1985 to 2016 without a joinpoint. Following the demographic and tumor characteristics, the trends of incidence and incidence-based mortality exhibited similar patterns. CONCLUSION: Considering various characteristics (age, sex, race, tumor location, SEER Historic Stage A, and histologic type), we established that the incidence trend of bone lymphoma has sharply been increasing over the decades, however, in the recent years, the trend has stabilized. Besides, between 1985 and 2016, the incidence-based mortality had been sharply increasing without a turning point. These findings could give insights for clinicians to elaborately assess the epidemiology and risk factors of bone lymphoma. |
format | Online Article Text |
id | pubmed-7390813 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-73908132020-08-04 The incidence and mortality trends of bone lymphoma in the United States: An analysis of the Surveillance, Epidemiology, and End Results database Xu, Daoliang Wang, Ben Chen, Lijie Zhang, Huawei Wang, Xiangyang Chen, Jiaoxiang J Bone Oncol Research Article BACKGROUND: In recent years, studies on bone lymphoma and its histologic types have reached a mature stage. However, reports on the incidence and incidence-based mortality trends of bone lymphoma are scanty. METHODS: Patients with bone lymphoma in the U.S. were selected from Surveillance, Epidemiology, and End Results (SEER) database (1975–2016), and categorized based on age, sex, race, tumor location, SEER Historic Stage A and histologic type. Data on the incidence (1975–2016) and incidence-based mortality (1985–2016) were directly obtained from the SEER program. Annual percentage change (APC) and 95% confidence intervals (CIs) were calculated using the joinpoint regression analysis program. RESULTS: Overall, 13,058 bone lymphoma cases diagnosed in resident patients of the U.S. were included in incidence analysis between 1975 and 2016 as follows: 6080 cases in 1975–1999, 3796 cases in 2000–2009, and 3182 cases in 2010–2016. Of these cases, 6888 died of bone lymphoma between 1985 and 2016. The overall incidence rates dramatically increased from 0.89 per 100,000 person-years in 1975 to 1.36 per 100,000 person-years in 2016. Incidence trend sharply increased from 1975 to 2009, and then stabilized between 2009 and 2016. Overall incidence-based mortality trends sharply increased from 1985 to 2016 without a joinpoint. Following the demographic and tumor characteristics, the trends of incidence and incidence-based mortality exhibited similar patterns. CONCLUSION: Considering various characteristics (age, sex, race, tumor location, SEER Historic Stage A, and histologic type), we established that the incidence trend of bone lymphoma has sharply been increasing over the decades, however, in the recent years, the trend has stabilized. Besides, between 1985 and 2016, the incidence-based mortality had been sharply increasing without a turning point. These findings could give insights for clinicians to elaborately assess the epidemiology and risk factors of bone lymphoma. Elsevier 2020-07-17 /pmc/articles/PMC7390813/ /pubmed/32760645 http://dx.doi.org/10.1016/j.jbo.2020.100306 Text en © 2020 The Author(s) http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Research Article Xu, Daoliang Wang, Ben Chen, Lijie Zhang, Huawei Wang, Xiangyang Chen, Jiaoxiang The incidence and mortality trends of bone lymphoma in the United States: An analysis of the Surveillance, Epidemiology, and End Results database |
title | The incidence and mortality trends of bone lymphoma in the United States: An analysis of the Surveillance, Epidemiology, and End Results database |
title_full | The incidence and mortality trends of bone lymphoma in the United States: An analysis of the Surveillance, Epidemiology, and End Results database |
title_fullStr | The incidence and mortality trends of bone lymphoma in the United States: An analysis of the Surveillance, Epidemiology, and End Results database |
title_full_unstemmed | The incidence and mortality trends of bone lymphoma in the United States: An analysis of the Surveillance, Epidemiology, and End Results database |
title_short | The incidence and mortality trends of bone lymphoma in the United States: An analysis of the Surveillance, Epidemiology, and End Results database |
title_sort | incidence and mortality trends of bone lymphoma in the united states: an analysis of the surveillance, epidemiology, and end results database |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7390813/ https://www.ncbi.nlm.nih.gov/pubmed/32760645 http://dx.doi.org/10.1016/j.jbo.2020.100306 |
work_keys_str_mv | AT xudaoliang theincidenceandmortalitytrendsofbonelymphomaintheunitedstatesananalysisofthesurveillanceepidemiologyandendresultsdatabase AT wangben theincidenceandmortalitytrendsofbonelymphomaintheunitedstatesananalysisofthesurveillanceepidemiologyandendresultsdatabase AT chenlijie theincidenceandmortalitytrendsofbonelymphomaintheunitedstatesananalysisofthesurveillanceepidemiologyandendresultsdatabase AT zhanghuawei theincidenceandmortalitytrendsofbonelymphomaintheunitedstatesananalysisofthesurveillanceepidemiologyandendresultsdatabase AT wangxiangyang theincidenceandmortalitytrendsofbonelymphomaintheunitedstatesananalysisofthesurveillanceepidemiologyandendresultsdatabase AT chenjiaoxiang theincidenceandmortalitytrendsofbonelymphomaintheunitedstatesananalysisofthesurveillanceepidemiologyandendresultsdatabase AT xudaoliang incidenceandmortalitytrendsofbonelymphomaintheunitedstatesananalysisofthesurveillanceepidemiologyandendresultsdatabase AT wangben incidenceandmortalitytrendsofbonelymphomaintheunitedstatesananalysisofthesurveillanceepidemiologyandendresultsdatabase AT chenlijie incidenceandmortalitytrendsofbonelymphomaintheunitedstatesananalysisofthesurveillanceepidemiologyandendresultsdatabase AT zhanghuawei incidenceandmortalitytrendsofbonelymphomaintheunitedstatesananalysisofthesurveillanceepidemiologyandendresultsdatabase AT wangxiangyang incidenceandmortalitytrendsofbonelymphomaintheunitedstatesananalysisofthesurveillanceepidemiologyandendresultsdatabase AT chenjiaoxiang incidenceandmortalitytrendsofbonelymphomaintheunitedstatesananalysisofthesurveillanceepidemiologyandendresultsdatabase |