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The Multifaceted Nature of Aminopeptidases ERAP1, ERAP2, and LNPEP: From Evolution to Disease
In the human genome, the aminopeptidases ERAP1, ERAP2 and LNPEP lie contiguously on chromosome 5. They share sequence homology, functions and associations with immune-mediated diseases. By analyzing their multifaceted activities as well as their expression in the zoological scale, we suggest here th...
Autores principales: | Paladini, Fabiana, Fiorillo, Maria Teresa, Tedeschi, Valentina, Mattorre, Benedetta, Sorrentino, Rosa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7390905/ https://www.ncbi.nlm.nih.gov/pubmed/32793222 http://dx.doi.org/10.3389/fimmu.2020.01576 |
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