Inhibiting Histone Deacetylases in Human Macrophages Promotes Glycolysis, IL-1β, and T Helper Cell Responses to Mycobacterium tuberculosis

Tuberculosis (TB) is the leading infectious killer in the world. Mycobacterium tuberculosis (Mtb), the bacteria that causes the disease, is phagocytosed by alveolar macrophages (AM) and infiltrating monocyte-derived macrophages (MDM) in the lung. Infected macrophages then upregulate effector functio...

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Detalles Bibliográficos
Autores principales: Cox, Donal J., Coleman, Amy M., Gogan, Karl M., Phelan, James J., Ó Maoldomhnaigh, Cilian, Dunne, Pádraic J., Basdeo, Sharee A., Keane, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7390906/
https://www.ncbi.nlm.nih.gov/pubmed/32793237
http://dx.doi.org/10.3389/fimmu.2020.01609

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7390906/
https://www.ncbi.nlm.nih.gov/pubmed/32793237
http://dx.doi.org/10.3389/fimmu.2020.01609

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