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In vitro and in vivo identification of clinically approved drugs that modify ACE2 expression

The COVID‐19 pandemic caused by SARS‐CoV‐2 has is a global health challenge. Angiotensin‐converting enzyme 2 (ACE2) is the host receptor for SARS‐CoV‐2 entry. Recent studies have suggested that patients with hypertension and diabetes treated with ACE inhibitors (ACEIs) or angiotensin receptor blocke...

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Detalles Bibliográficos
Autores principales: Sinha, Sanju, Cheng, Kuoyuan, Schäffer, Alejandro A, Aldape, Kenneth, Schiff, Eyal, Ruppin, Eytan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7390914/
https://www.ncbi.nlm.nih.gov/pubmed/32729248
http://dx.doi.org/10.15252/msb.20209628

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