Cargando…
NVP-CGM097, an HDM2 Inhibitor, Antagonizes ATP-Binding Cassette Subfamily B Member 1-Mediated Drug Resistance
Multidrug resistance (MDR) is a major challenge in the treatment of tumors. It refers to cancer cells become resistant to not only the therapeutic drug, but also cross-resistant to multiple drugs with distinct structures and mechanisms of action when they are exposed to a drug for a period of time....
Autores principales: | Zhang, Meng, Chen, Xuan-Yu, Dong, Xing-Duo, Wang, Jing-Quan, Feng, Weiguo, Teng, Qiu-Xu, Cui, Qingbin, Li, Jing, Li, Xiang-Qi, Chen, Zhe-Sheng |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7390918/ https://www.ncbi.nlm.nih.gov/pubmed/32793491 http://dx.doi.org/10.3389/fonc.2020.01219 |
Ejemplares similares
-
A distinct p53 target gene set predicts for response to the selective p53–HDM2 inhibitor NVP-CGM097
por: Jeay, Sébastien, et al.
Publicado: (2015) -
Correction: A distinct p53 target gene set predicts for response to the selective p53-HDM2 inhibitor NVP-CGM097
por: Jeay, Sébastien, et al.
Publicado: (2016) -
Masitinib antagonizes ATP-binding cassette subfamily G member 2-mediated multidrug resistance
por: KATHAWALA, RISHIL J., et al.
Publicado: (2014) -
Pharmacokinetic–pharmacodynamic guided optimisation of dose and schedule of CGM097, an HDM2 inhibitor, in preclinical and clinical studies
por: Bauer, Sebastian, et al.
Publicado: (2021) -
A 20(S)-protopanoxadiol derivative overcomes multi-drug resistance by antagonizing ATP-binding cassette subfamily B member 1 transporter function
por: Chen, Gang, et al.
Publicado: (2016)