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Valeriana officinalis Counteracts Rotenone Effects on Spreading Depression in the Rat Brain in vivo and Protects Against Rotenone Cytotoxicity Toward Rat Glioma C6 Cells in vitro
Astrocytes can protect neurons against oxidative stress and excitability-dependent disorders, such as epilepsy. Valeriana officinalis has been used as anticonvulsant and can exert an antioxidant effect, which may underlie its opposing action against the toxic effects of the pesticide rotenone. We in...
Autores principales: | Amaral de Brito, Ana Paula, Galvão de Melo, Isabel Michely da Silva, El-Bachá, Ramon Santos, Guedes, Rubem Carlos Araújo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7390944/ https://www.ncbi.nlm.nih.gov/pubmed/32792901 http://dx.doi.org/10.3389/fnins.2020.00759 |
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