Multimodal Analysis of Composition and Spatial Architecture in Human Squamous Cell Carcinoma

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To define the cellular composition and architecture of cutaneous squamous cell carcinoma (cSCC), we combined single-cell RNA sequencing with spatial transcriptomics and multiplexed ion beam imaging from a series of human cSCCs and matched normal skin. cSCC exhibited four tumor subpopulations, three...

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Detalles Bibliográficos
Autores principales: Ji, Andrew L., Rubin, Adam J., Thrane, Kim, Jiang, Sizun, Reynolds, David L., Meyers, Robin M., Guo, Margaret G., George, Benson M., Mollbrink, Annelie, Bergenstråhle, Joseph, Larsson, Ludvig, Bai, Yunhao, Zhu, Bokai, Bhaduri, Aparna, Meyers, Jordan M., Rovira-Clavé, Xavier, Hollmig, S. Tyler, Aasi, Sumaira Z., Nolan, Garry P., Lundeberg, Joakim, Khavari, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7391009/
https://www.ncbi.nlm.nih.gov/pubmed/32579974
http://dx.doi.org/10.1016/j.cell.2020.05.039
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