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The Clinical Application of Core-Needle Biopsy after Radiofrequency Ablation for Low-risk Papillary Thyroid Microcarcinoma: A Large Cohort of 202 Patients Study
Purpose: To evaluate the clinical application of core-needle biopsy (CNB) for low-risk papillary thyroid microcarcinoma (PTMC) after radiofrequency ablation (RFA) Methods: A total of 202 patients with 211 low-risk PTMCs were included in this study. RFA procedure was used the hydrodissection techniqu...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Ivyspring International Publisher
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7391195/ https://www.ncbi.nlm.nih.gov/pubmed/32742471 http://dx.doi.org/10.7150/jca.42673 |
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author | Yan, Lin Luo, Yukun Zhang, Ying Zhu, Yaqiong Xiao, Jing Lan, Yu Tian, Xiaoqi Song, Qing Xie, Fang |
author_facet | Yan, Lin Luo, Yukun Zhang, Ying Zhu, Yaqiong Xiao, Jing Lan, Yu Tian, Xiaoqi Song, Qing Xie, Fang |
author_sort | Yan, Lin |
collection | PubMed |
description | Purpose: To evaluate the clinical application of core-needle biopsy (CNB) for low-risk papillary thyroid microcarcinoma (PTMC) after radiofrequency ablation (RFA) Methods: A total of 202 patients with 211 low-risk PTMCs were included in this study. RFA procedure was used the hydrodissection technique and moving-shot technique. Patients were followed at 1, 3, 6, 12 months and every 6 months thereafter. The volume of ablation area and the volume reduction ratio (VRR) were calculated. At 3 or 6 months after RFA, CNB was performed to the central zone, the peripheral zone and surrounding thyroid parenchyma for post-ablation evaluation. Results: The mean volume of tumors was 102.34±93.84 mm(3) (range 4.19-424.10 mm(3)), which decreased significantly to 1.37±7.74 mm(3) (range 0-73.30 mm(3)) at a mean follow-up time of 24.42±9.15 months (range 3-42 months) with a mean VRR of 99.14±4.18% (range 71.88-100%). A total of 3 ablation areas had positive CNB in the peripheral zone and underwent additional RFA. No recurrent or suspicious metastatic lymph nodes were detected Conclusion: CNB is a feasible and effective evaluation for low-risk PTMC after RFA, which can detect residual cancer cells early. |
format | Online Article Text |
id | pubmed-7391195 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Ivyspring International Publisher |
record_format | MEDLINE/PubMed |
spelling | pubmed-73911952020-07-31 The Clinical Application of Core-Needle Biopsy after Radiofrequency Ablation for Low-risk Papillary Thyroid Microcarcinoma: A Large Cohort of 202 Patients Study Yan, Lin Luo, Yukun Zhang, Ying Zhu, Yaqiong Xiao, Jing Lan, Yu Tian, Xiaoqi Song, Qing Xie, Fang J Cancer Research Paper Purpose: To evaluate the clinical application of core-needle biopsy (CNB) for low-risk papillary thyroid microcarcinoma (PTMC) after radiofrequency ablation (RFA) Methods: A total of 202 patients with 211 low-risk PTMCs were included in this study. RFA procedure was used the hydrodissection technique and moving-shot technique. Patients were followed at 1, 3, 6, 12 months and every 6 months thereafter. The volume of ablation area and the volume reduction ratio (VRR) were calculated. At 3 or 6 months after RFA, CNB was performed to the central zone, the peripheral zone and surrounding thyroid parenchyma for post-ablation evaluation. Results: The mean volume of tumors was 102.34±93.84 mm(3) (range 4.19-424.10 mm(3)), which decreased significantly to 1.37±7.74 mm(3) (range 0-73.30 mm(3)) at a mean follow-up time of 24.42±9.15 months (range 3-42 months) with a mean VRR of 99.14±4.18% (range 71.88-100%). A total of 3 ablation areas had positive CNB in the peripheral zone and underwent additional RFA. No recurrent or suspicious metastatic lymph nodes were detected Conclusion: CNB is a feasible and effective evaluation for low-risk PTMC after RFA, which can detect residual cancer cells early. Ivyspring International Publisher 2020-07-09 /pmc/articles/PMC7391195/ /pubmed/32742471 http://dx.doi.org/10.7150/jca.42673 Text en © The author(s) This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/). See http://ivyspring.com/terms for full terms and conditions. |
spellingShingle | Research Paper Yan, Lin Luo, Yukun Zhang, Ying Zhu, Yaqiong Xiao, Jing Lan, Yu Tian, Xiaoqi Song, Qing Xie, Fang The Clinical Application of Core-Needle Biopsy after Radiofrequency Ablation for Low-risk Papillary Thyroid Microcarcinoma: A Large Cohort of 202 Patients Study |
title | The Clinical Application of Core-Needle Biopsy after Radiofrequency Ablation for Low-risk Papillary Thyroid Microcarcinoma: A Large Cohort of 202 Patients Study |
title_full | The Clinical Application of Core-Needle Biopsy after Radiofrequency Ablation for Low-risk Papillary Thyroid Microcarcinoma: A Large Cohort of 202 Patients Study |
title_fullStr | The Clinical Application of Core-Needle Biopsy after Radiofrequency Ablation for Low-risk Papillary Thyroid Microcarcinoma: A Large Cohort of 202 Patients Study |
title_full_unstemmed | The Clinical Application of Core-Needle Biopsy after Radiofrequency Ablation for Low-risk Papillary Thyroid Microcarcinoma: A Large Cohort of 202 Patients Study |
title_short | The Clinical Application of Core-Needle Biopsy after Radiofrequency Ablation for Low-risk Papillary Thyroid Microcarcinoma: A Large Cohort of 202 Patients Study |
title_sort | clinical application of core-needle biopsy after radiofrequency ablation for low-risk papillary thyroid microcarcinoma: a large cohort of 202 patients study |
topic | Research Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7391195/ https://www.ncbi.nlm.nih.gov/pubmed/32742471 http://dx.doi.org/10.7150/jca.42673 |
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