MicroRNA-154-5p regulates the HPV16 E7-pRb pathway in Cervical Carcinogenesis by targeting CUL2

Cervical cancer, induced by persistent HPV infection, has a high mortality rate. The E3 ubiquitin ligase Cullin 2 (CUL2) is critical for HPV16 E7-mediated degradation of retinoblastoma protein (pRb). Dysregulation of microRNAs (miRNAs) is induced during tumorigenesis; however, the association betwee...

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Detalles Bibliográficos
Autores principales: Zhao, Weihong, Liu, Yatao, Zhang, Lili, Ding, Ling, Li, Yaqin, Zhang, Honglei, Wang, Tong, Hao, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7391205/
https://www.ncbi.nlm.nih.gov/pubmed/32742484
http://dx.doi.org/10.7150/jca.45871

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7391205/
https://www.ncbi.nlm.nih.gov/pubmed/32742484
http://dx.doi.org/10.7150/jca.45871

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