Cargando…

BCAS1-positive immature oligodendrocytes are affected by the α-synuclein-induced pathology of multiple system atrophy

Multiple system atrophy (MSA) is pathologically characterized by the presence of fibrillar α-synuclein-immunoreactive inclusions in oligodendrocytes. Although the myelinating process of oligodendrocytes can be observed in adult human brains, little is known regarding the presence of α-synuclein path...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kaji, Seiji, Maki, Takakuni, Ueda, Jun, Ishimoto, Tomoyuki, Inoue, Yutaka, Yasuda, Ken, Sawamura, Masanori, Hikawa, Rie, Ayaki, Takashi, Yamakado, Hodaka, Takahashi, Ryosuke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7391509/ https://www.ncbi.nlm.nih.gov/pubmed/32727582 http://dx.doi.org/10.1186/s40478-020-00997-4

Ejemplares similares

Insights into the pathogenesis of multiple system atrophy: focus on glial cytoplasmic inclusions
por: Kaji, Seiji, et al.
Publicado: (2020)

Pathological Endogenous α-Synuclein Accumulation in Oligodendrocyte Precursor Cells Potentially Induces Inclusions in Multiple System Atrophy
por: Kaji, Seiji, et al.
Publicado: (2018)

Striatal-Inoculation of α-Synuclein Preformed Fibrils Aggravated the Phenotypes of REM Sleep without Atonia in A53T BAC-SNCA Transgenic Mice
por: Okuda, Shinya, et al.
Publicado: (2022)

Homozygous 31 trinucleotide repeats in the SCA2 allele are pathogenic for cerebellar ataxia
por: Tojima, Maya, et al.
Publicado: (2018)

CUL2-mediated clearance of misfolded TDP-43 is paradoxically affected by VHL in oligodendrocytes in ALS
por: Uchida, Tsukasa, et al.
Publicado: (2016)

Non-aneurysmal Subarachnoid Hemorrhaging: A Rare Cause of Death in a Patient with Multiple System Atrophy
por: Kinoshita, Hisanori, et al.
Publicado: (2019)

Impact of Gba2 on neuronopathic Gaucher’s disease and α-synuclein accumulation in medaka (Oryzias latipes)
por: Nakanishi, Etsuro, et al.
Publicado: (2021)

Susceptibility to erastin‐induced ferroptosis decreases during maturation in a human oligodendrocyte cell line
por: Hoshino, Tomonori, et al.
Publicado: (2020)

DOPAnization of tyrosine in α-synuclein by tyrosine hydroxylase leads to the formation of oligomers
por: Jin, Mingyue, et al.
Publicado: (2022)

Role of Perivascular Oligodendrocyte Precursor Cells in Angiogenesis After Brain Ischemia
por: Kishida, Natsue, et al.
Publicado: (2019)

Cellular analysis of SOD1 protein-aggregation propensity and toxicity: a case of ALS with slow progression harboring homozygous SOD1-D92G mutation
por: Sawamura, Masanori, et al.
Publicado: (2022)

Multiple system atrophy: α-Synuclein strains at the neuron-oligodendrocyte crossroad
por: Reddy, Kreesan, et al.
Publicado: (2022)

Unilateral Hypoglossal Nerve Palsy: A Hidden Tumor
por: Sawamura, Masanori, et al.
Publicado: (2019)

Developmental Changes in Dendritic Spine Morphology in the Striatum and Their Alteration in an A53T α-Synuclein Transgenic Mouse Model of Parkinson’s Disease
por: Parajuli, Laxmi Kumar, et al.
Publicado: (2020)

Inoculation of α-synuclein preformed fibrils into the mouse gastrointestinal tract induces Lewy body-like aggregates in the brainstem via the vagus nerve
por: Uemura, Norihito, et al.
Publicado: (2018)

Correction to: Inoculation of α-synuclein preformed fibrils into the mouse gastrointestinal tract induces Lewy body-like aggregates in the brainstem via the vagus nerve
por: Uemura, Norihito, et al.
Publicado: (2019)

Animal Model for Prodromal Parkinson’s Disease
por: Taguchi, Tomoyuki, et al.
Publicado: (2020)

High Mobility Group A1 Regulates Transcription Levels of Oligodendrocyte Marker Genes in Cultured Oligodendrocyte Precursor Cells
por: Egawa, Naohiro, et al.
Publicado: (2022)

FAS-Dependent Cell Death in α-Synuclein Transgenic Oligodendrocyte Models of Multiple System Atrophy
por: Kragh, Christine L., et al.
Publicado: (2013)

Two cases of delayed perforating artery infarction adjacent to intracranial hemorrhage
por: Yasuda, Ken, et al.
Publicado: (2019)

Rudhira/BCAS3 is essential for mouse development and cardiovascular patterning
por: Shetty, Ronak, et al.
Publicado: (2018)

Overexpression of α-Synuclein by Oligodendrocytes in Transgenic Mice Does Not Recapitulate the Fibrillar Aggregation Seen in Multiple System Atrophy
por: Laferrière, Florent, et al.
Publicado: (2020)

Efficacy of oligodendrocyte precursor cells as delivery vehicles for single-chain variable fragment to misfolded SOD1 in ALS rat model
por: Minamiyama, Sumio, et al.
Publicado: (2023)

Alpha-Synuclein Inclusion Formation in Human Oligodendrocytes
por: Yoon, Ye-Seul, et al.
Publicado: (2021)

Validation of an Indonesian Version of the Breast Cancer Awareness Scale (BCAS-I)
por: Solikhah, Solikhah, et al.
Publicado: (2017)

Utility of Skeletal Muscle CT in Diagnosing Spinal Muscular Atrophy Type 3 in a Patient Who Had Been Undiagnosed for 50 Years
por: Hirayama, Michihiro, et al.
Publicado: (2023)

Amyotrophic Lateral Sclerosis after Receiving the Human Papilloma Virus Vaccine: A Case Report of a 15-year-old Girl
por: Hikiami, Ryota, et al.
Publicado: (2018)

Cellular internalization of alpha-synuclein aggregates by cell surface heparan sulfate depends on aggregate conformation and cell type
por: Ihse, Elisabet, et al.
Publicado: (2017)

Viable Neuronopathic Gaucher Disease Model in Medaka (Oryzias latipes) Displays Axonal Accumulation of Alpha-Synuclein
por: Uemura, Norihito, et al.
Publicado: (2015)

Mechanisms of oligodendrocyte regeneration from ventricular-subventricular zone-derived progenitor cells in white matter diseases
por: Maki, Takakuni, et al.
Publicado: (2013)

Alpha-synuclein mRNA expression in oligodendrocytes in MSA
por: Asi, Yasmine T, et al.
Publicado: (2014)

BCAS2 is involved in alternative mRNA splicing in spermatogonia and the transition to meiosis
por: Liu, Wenbo, et al.
Publicado: (2017)

Oligodendrocytes Prune Axons Containing α-Synuclein Aggregates In Vivo: Lewy Neurites as Precursors of Glial Cytoplasmic Inclusions in Multiple System Atrophy?
por: De Nuccio, Francesco, et al.
Publicado: (2023)

BCAS2 Enhances Carcinogenic Effects of Estrogen Receptor Alpha in Breast Cancer Cells
por: Salmerón-Hernández, Ángel, et al.
Publicado: (2019)

BCAS2 regulates granulosa cell survival by participating in mRNA alternative splicing
por: Yao, Xiaohong, et al.
Publicado: (2023)

Role of Oligodendrocyte Lineage Cells in Multiple System Atrophy
por: Hsiao, Jen-Hsiang T., et al.
Publicado: (2023)

Pericyte‐derived bone morphogenetic protein 4 underlies white matter damage after chronic hypoperfusion
por: Uemura, Maiko T., et al.
Publicado: (2017)

Rudhira/BCAS3 couples microtubules and intermediate filaments to promote cell migration for angiogenic remodeling
por: Joshi, Divyesh, et al.
Publicado: (2019)

Overexpression of a Pak Choi Gene, BcAS2, Causes Leaf Curvature in Arabidopsis thaliana
por: Lin, Ye, et al.
Publicado: (2021)

The proppin Bcas3 and its interactor KinkyA localize to the early phagophore and regulate autophagy
por: Yamada, Yoko, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_mqh61ecskfs5fstvmq7lqq3aqi