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Cardiovascular risk screening of patients with serious mental illness or use of antipsychotics in family practice

BACKGROUND: Patients with serious mental illness (SMI) and patients on antipsychotics (AP) have an elevated risk for cardiovascular diseases. In the Netherlands, the mental healthcare for these patients is increasingly taken care of by family practitioners (FP) as a result of a shift from secondary...

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Autores principales: Jakobs, Kirsti M., Posthuma, Anne, de Grauw, Wim J. C., Schalk, Bianca W. M., Akkermans, Reinier P., Lucassen, Peter, Schermer, Tjard, Assendelft, Willem J. J., Biermans, Marion J. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7391510/
https://www.ncbi.nlm.nih.gov/pubmed/32727372
http://dx.doi.org/10.1186/s12875-020-01225-7
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author Jakobs, Kirsti M.
Posthuma, Anne
de Grauw, Wim J. C.
Schalk, Bianca W. M.
Akkermans, Reinier P.
Lucassen, Peter
Schermer, Tjard
Assendelft, Willem J. J.
Biermans, Marion J. C.
author_facet Jakobs, Kirsti M.
Posthuma, Anne
de Grauw, Wim J. C.
Schalk, Bianca W. M.
Akkermans, Reinier P.
Lucassen, Peter
Schermer, Tjard
Assendelft, Willem J. J.
Biermans, Marion J. C.
author_sort Jakobs, Kirsti M.
collection PubMed
description BACKGROUND: Patients with serious mental illness (SMI) and patients on antipsychotics (AP) have an elevated risk for cardiovascular diseases. In the Netherlands, the mental healthcare for these patients is increasingly taken care of by family practitioners (FP) as a result of a shift from secondary to primary care. Therefore, it is essential to increase our knowledge regarding the characteristics of this patient group and the (somatic) care provided by their FPs. The aim was to examine the rate of cardiovascular risk screening in patients with SMI or the use of AP in family practice. METHODS: We performed a retrospective cohort study of 151.238 patients listed in 24 family practices in the Netherlands. From electronic medical records we extracted data concerning diagnoses, measurement values of CVR factors, medication and frequency of visits over a 2 year period. Primary outcome was the rate of patients who were screened for CVR factors. We compared three groups: patients with SMI/AP without diabetes or CVD (SMI/AP-only), patients with SMI/AP and diabetes mellitus (SMI/AP + DM), patients with SMI/AP and a history of cardiovascular disease (SMI/AP + CVD). We explored factors associated with adequate screening using multilevel logistic regression. RESULTS: We identified 1705 patients with SMI/AP, 834 with a SMI diagnosis, 1150 using AP. The screening rate for CVR in the SMI/AP-only group (n = 1383) was adequate in 8.5%. Screening was higher in the SMI/AP − +DM (n = 206, 68.4% adequate, OR 24.6 (95%CI, 17.3–35.1) and SMI/AP + CVD (n = 116, 26.7% adequate, OR 4.2 (95%CI, 2.7–6.6). A high frequency of visits, age, the use of AP and a diagnosis of COPD were associated with a higher screening rate. In addition we also examined differences between patients with SMI and patients using AP without SMI. CONCLUSION: CVR screening in patients with SMI/AP is performed poorly in Dutch family practices. Acceptable screening rates were found only among SMI/AP patients with diabetes mellitus as comorbidity. The finding of a large group of AP users without a SMI diagnosis may indicate that FPs often prescribe AP off-label, lack information about the diagnosis, or use the wrong code.
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spelling pubmed-73915102020-07-31 Cardiovascular risk screening of patients with serious mental illness or use of antipsychotics in family practice Jakobs, Kirsti M. Posthuma, Anne de Grauw, Wim J. C. Schalk, Bianca W. M. Akkermans, Reinier P. Lucassen, Peter Schermer, Tjard Assendelft, Willem J. J. Biermans, Marion J. C. BMC Fam Pract Research Article BACKGROUND: Patients with serious mental illness (SMI) and patients on antipsychotics (AP) have an elevated risk for cardiovascular diseases. In the Netherlands, the mental healthcare for these patients is increasingly taken care of by family practitioners (FP) as a result of a shift from secondary to primary care. Therefore, it is essential to increase our knowledge regarding the characteristics of this patient group and the (somatic) care provided by their FPs. The aim was to examine the rate of cardiovascular risk screening in patients with SMI or the use of AP in family practice. METHODS: We performed a retrospective cohort study of 151.238 patients listed in 24 family practices in the Netherlands. From electronic medical records we extracted data concerning diagnoses, measurement values of CVR factors, medication and frequency of visits over a 2 year period. Primary outcome was the rate of patients who were screened for CVR factors. We compared three groups: patients with SMI/AP without diabetes or CVD (SMI/AP-only), patients with SMI/AP and diabetes mellitus (SMI/AP + DM), patients with SMI/AP and a history of cardiovascular disease (SMI/AP + CVD). We explored factors associated with adequate screening using multilevel logistic regression. RESULTS: We identified 1705 patients with SMI/AP, 834 with a SMI diagnosis, 1150 using AP. The screening rate for CVR in the SMI/AP-only group (n = 1383) was adequate in 8.5%. Screening was higher in the SMI/AP − +DM (n = 206, 68.4% adequate, OR 24.6 (95%CI, 17.3–35.1) and SMI/AP + CVD (n = 116, 26.7% adequate, OR 4.2 (95%CI, 2.7–6.6). A high frequency of visits, age, the use of AP and a diagnosis of COPD were associated with a higher screening rate. In addition we also examined differences between patients with SMI and patients using AP without SMI. CONCLUSION: CVR screening in patients with SMI/AP is performed poorly in Dutch family practices. Acceptable screening rates were found only among SMI/AP patients with diabetes mellitus as comorbidity. The finding of a large group of AP users without a SMI diagnosis may indicate that FPs often prescribe AP off-label, lack information about the diagnosis, or use the wrong code. BioMed Central 2020-07-29 /pmc/articles/PMC7391510/ /pubmed/32727372 http://dx.doi.org/10.1186/s12875-020-01225-7 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Article
Jakobs, Kirsti M.
Posthuma, Anne
de Grauw, Wim J. C.
Schalk, Bianca W. M.
Akkermans, Reinier P.
Lucassen, Peter
Schermer, Tjard
Assendelft, Willem J. J.
Biermans, Marion J. C.
Cardiovascular risk screening of patients with serious mental illness or use of antipsychotics in family practice
title Cardiovascular risk screening of patients with serious mental illness or use of antipsychotics in family practice
title_full Cardiovascular risk screening of patients with serious mental illness or use of antipsychotics in family practice
title_fullStr Cardiovascular risk screening of patients with serious mental illness or use of antipsychotics in family practice
title_full_unstemmed Cardiovascular risk screening of patients with serious mental illness or use of antipsychotics in family practice
title_short Cardiovascular risk screening of patients with serious mental illness or use of antipsychotics in family practice
title_sort cardiovascular risk screening of patients with serious mental illness or use of antipsychotics in family practice
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7391510/
https://www.ncbi.nlm.nih.gov/pubmed/32727372
http://dx.doi.org/10.1186/s12875-020-01225-7
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