Altered mechanisms of genital development identified through integration of DNA methylation and genomic measures in hypospadias

Hypospadias is a common birth defect where the urethral opening forms on the ventral side of the penis. We performed integrative methylomic, genomic, and transcriptomic analyses to characterize sites of DNA methylation that influence genital development. In case–control and case-only epigenome-wide...

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Detalles Bibliográficos
Autores principales: Richard, Melissa A., Sok, Pagna, Canon, Stephen, Nembhard, Wendy N., Brown, Austin L., Peckham-Gregory, Erin C., Ton, Minh, Ehli, Erik A., Kallsen, Noah A., Peyton, Shanna A., Davies, Gareth E., Patel, Ashay, Zamilpa, Ismael, Hobbs, Charlotte A., Scheurer, Michael E., Lupo, Philip J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7391634/
https://www.ncbi.nlm.nih.gov/pubmed/32728162
http://dx.doi.org/10.1038/s41598-020-69725-1

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