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Survival differences and associated molecular signatures of DNMT3A-mutant acute myeloid leukemia patients

Acute myeloid leukemia (AML) is a very heterogeneous and highly malignant blood cancer. Mutations of the DNA methyltransferase DNMT3A are among the most frequent recurrent genetic lesions in AML. The majority of DNMT3A-mutant AML patients shows fast relapse and poor survival, but also patients with...

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Detalles Bibliográficos
Autores principales:	Lauber, Chris, Correia, Nádia, Trumpp, Andreas, Rieger, Michael A., Dolnik, Anna, Bullinger, Lars, Roeder, Ingo, Seifert, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7391693/ https://www.ncbi.nlm.nih.gov/pubmed/32728112 http://dx.doi.org/10.1038/s41598-020-69691-8

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