Cargando…
Genetic and environmental variation in educational attainment: an individual-based analysis of 28 twin cohorts
We investigated the heritability of educational attainment and how it differed between birth cohorts and cultural–geographic regions. A classical twin design was applied to pooled data from 28 cohorts representing 16 countries and including 193,518 twins with information on educational attainment at...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7391756/ https://www.ncbi.nlm.nih.gov/pubmed/32728164 http://dx.doi.org/10.1038/s41598-020-69526-6 |
_version_ | 1783564716797329408 |
---|---|
author | Silventoinen, Karri Jelenkovic, Aline Sund, Reijo Latvala, Antti Honda, Chika Inui, Fujio Tomizawa, Rie Watanabe, Mikio Sakai, Norio Rebato, Esther Busjahn, Andreas Tyler, Jessica Hopper, John L. Ordoñana, Juan R. Sánchez-Romera, Juan F. Colodro-Conde, Lucia Calais-Ferreira, Lucas Oliveira, Vinicius C. Ferreira, Paulo H. Medda, Emanuela Nisticò, Lorenza Toccaceli, Virgilia Derom, Catherine A. Vlietinck, Robert F. Loos, Ruth J. F. Siribaddana, Sisira H. Hotopf, Matthew Sumathipala, Athula Rijsdijk, Fruhling Duncan, Glen E. Buchwald, Dedra Tynelius, Per Rasmussen, Finn Tan, Qihua Zhang, Dongfeng Pang, Zengchang Magnusson, Patrik K. E. Pedersen, Nancy L. Dahl Aslan, Anna K. Hwang, Amie E. Mack, Thomas M. Krueger, Robert F. McGue, Matt Pahlen, Shandell Brandt, Ingunn Nilsen, Thomas S. Harris, Jennifer R. Martin, Nicholas G. Medland, Sarah E. Montgomery, Grant W. Willemsen, Gonneke Bartels, Meike van Beijsterveldt, Catharina E. M. Franz, Carol E. Kremen, William S. Lyons, Michael J. Silberg, Judy L. Maes, Hermine H. Kandler, Christian Nelson, Tracy L. Whitfield, Keith E. Corley, Robin P. Huibregtse, Brooke M. Gatz, Margaret Butler, David A. Tarnoki, Adam D. Tarnoki, David L. Park, Hang A. Lee, Jooyeon Lee, Soo Ji Sung, Joohon Yokoyama, Yoshie Sørensen, Thorkild I. A. Boomsma, Dorret I. Kaprio, Jaakko |
author_facet | Silventoinen, Karri Jelenkovic, Aline Sund, Reijo Latvala, Antti Honda, Chika Inui, Fujio Tomizawa, Rie Watanabe, Mikio Sakai, Norio Rebato, Esther Busjahn, Andreas Tyler, Jessica Hopper, John L. Ordoñana, Juan R. Sánchez-Romera, Juan F. Colodro-Conde, Lucia Calais-Ferreira, Lucas Oliveira, Vinicius C. Ferreira, Paulo H. Medda, Emanuela Nisticò, Lorenza Toccaceli, Virgilia Derom, Catherine A. Vlietinck, Robert F. Loos, Ruth J. F. Siribaddana, Sisira H. Hotopf, Matthew Sumathipala, Athula Rijsdijk, Fruhling Duncan, Glen E. Buchwald, Dedra Tynelius, Per Rasmussen, Finn Tan, Qihua Zhang, Dongfeng Pang, Zengchang Magnusson, Patrik K. E. Pedersen, Nancy L. Dahl Aslan, Anna K. Hwang, Amie E. Mack, Thomas M. Krueger, Robert F. McGue, Matt Pahlen, Shandell Brandt, Ingunn Nilsen, Thomas S. Harris, Jennifer R. Martin, Nicholas G. Medland, Sarah E. Montgomery, Grant W. Willemsen, Gonneke Bartels, Meike van Beijsterveldt, Catharina E. M. Franz, Carol E. Kremen, William S. Lyons, Michael J. Silberg, Judy L. Maes, Hermine H. Kandler, Christian Nelson, Tracy L. Whitfield, Keith E. Corley, Robin P. Huibregtse, Brooke M. Gatz, Margaret Butler, David A. Tarnoki, Adam D. Tarnoki, David L. Park, Hang A. Lee, Jooyeon Lee, Soo Ji Sung, Joohon Yokoyama, Yoshie Sørensen, Thorkild I. A. Boomsma, Dorret I. Kaprio, Jaakko |
author_sort | Silventoinen, Karri |
collection | PubMed |
description | We investigated the heritability of educational attainment and how it differed between birth cohorts and cultural–geographic regions. A classical twin design was applied to pooled data from 28 cohorts representing 16 countries and including 193,518 twins with information on educational attainment at 25 years of age or older. Genetic factors explained the major part of individual differences in educational attainment (heritability: a(2) = 0.43; 0.41–0.44), but also environmental variation shared by co-twins was substantial (c(2) = 0.31; 0.30–0.33). The proportions of educational variation explained by genetic and shared environmental factors did not differ between Europe, North America and Australia, and East Asia. When restricted to twins 30 years or older to confirm finalized education, the heritability was higher in the older cohorts born in 1900–1949 (a(2) = 0.44; 0.41–0.46) than in the later cohorts born in 1950–1989 (a(2) = 0.38; 0.36–0.40), with a corresponding lower influence of common environmental factors (c(2) = 0.31; 0.29–0.33 and c(2) = 0.34; 0.32–0.36, respectively). In conclusion, both genetic and environmental factors shared by co-twins have an important influence on individual differences in educational attainment. The effect of genetic factors on educational attainment has decreased from the cohorts born before to those born after the 1950s. |
format | Online Article Text |
id | pubmed-7391756 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-73917562020-07-31 Genetic and environmental variation in educational attainment: an individual-based analysis of 28 twin cohorts Silventoinen, Karri Jelenkovic, Aline Sund, Reijo Latvala, Antti Honda, Chika Inui, Fujio Tomizawa, Rie Watanabe, Mikio Sakai, Norio Rebato, Esther Busjahn, Andreas Tyler, Jessica Hopper, John L. Ordoñana, Juan R. Sánchez-Romera, Juan F. Colodro-Conde, Lucia Calais-Ferreira, Lucas Oliveira, Vinicius C. Ferreira, Paulo H. Medda, Emanuela Nisticò, Lorenza Toccaceli, Virgilia Derom, Catherine A. Vlietinck, Robert F. Loos, Ruth J. F. Siribaddana, Sisira H. Hotopf, Matthew Sumathipala, Athula Rijsdijk, Fruhling Duncan, Glen E. Buchwald, Dedra Tynelius, Per Rasmussen, Finn Tan, Qihua Zhang, Dongfeng Pang, Zengchang Magnusson, Patrik K. E. Pedersen, Nancy L. Dahl Aslan, Anna K. Hwang, Amie E. Mack, Thomas M. Krueger, Robert F. McGue, Matt Pahlen, Shandell Brandt, Ingunn Nilsen, Thomas S. Harris, Jennifer R. Martin, Nicholas G. Medland, Sarah E. Montgomery, Grant W. Willemsen, Gonneke Bartels, Meike van Beijsterveldt, Catharina E. M. Franz, Carol E. Kremen, William S. Lyons, Michael J. Silberg, Judy L. Maes, Hermine H. Kandler, Christian Nelson, Tracy L. Whitfield, Keith E. Corley, Robin P. Huibregtse, Brooke M. Gatz, Margaret Butler, David A. Tarnoki, Adam D. Tarnoki, David L. Park, Hang A. Lee, Jooyeon Lee, Soo Ji Sung, Joohon Yokoyama, Yoshie Sørensen, Thorkild I. A. Boomsma, Dorret I. Kaprio, Jaakko Sci Rep Article We investigated the heritability of educational attainment and how it differed between birth cohorts and cultural–geographic regions. A classical twin design was applied to pooled data from 28 cohorts representing 16 countries and including 193,518 twins with information on educational attainment at 25 years of age or older. Genetic factors explained the major part of individual differences in educational attainment (heritability: a(2) = 0.43; 0.41–0.44), but also environmental variation shared by co-twins was substantial (c(2) = 0.31; 0.30–0.33). The proportions of educational variation explained by genetic and shared environmental factors did not differ between Europe, North America and Australia, and East Asia. When restricted to twins 30 years or older to confirm finalized education, the heritability was higher in the older cohorts born in 1900–1949 (a(2) = 0.44; 0.41–0.46) than in the later cohorts born in 1950–1989 (a(2) = 0.38; 0.36–0.40), with a corresponding lower influence of common environmental factors (c(2) = 0.31; 0.29–0.33 and c(2) = 0.34; 0.32–0.36, respectively). In conclusion, both genetic and environmental factors shared by co-twins have an important influence on individual differences in educational attainment. The effect of genetic factors on educational attainment has decreased from the cohorts born before to those born after the 1950s. Nature Publishing Group UK 2020-07-29 /pmc/articles/PMC7391756/ /pubmed/32728164 http://dx.doi.org/10.1038/s41598-020-69526-6 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Silventoinen, Karri Jelenkovic, Aline Sund, Reijo Latvala, Antti Honda, Chika Inui, Fujio Tomizawa, Rie Watanabe, Mikio Sakai, Norio Rebato, Esther Busjahn, Andreas Tyler, Jessica Hopper, John L. Ordoñana, Juan R. Sánchez-Romera, Juan F. Colodro-Conde, Lucia Calais-Ferreira, Lucas Oliveira, Vinicius C. Ferreira, Paulo H. Medda, Emanuela Nisticò, Lorenza Toccaceli, Virgilia Derom, Catherine A. Vlietinck, Robert F. Loos, Ruth J. F. Siribaddana, Sisira H. Hotopf, Matthew Sumathipala, Athula Rijsdijk, Fruhling Duncan, Glen E. Buchwald, Dedra Tynelius, Per Rasmussen, Finn Tan, Qihua Zhang, Dongfeng Pang, Zengchang Magnusson, Patrik K. E. Pedersen, Nancy L. Dahl Aslan, Anna K. Hwang, Amie E. Mack, Thomas M. Krueger, Robert F. McGue, Matt Pahlen, Shandell Brandt, Ingunn Nilsen, Thomas S. Harris, Jennifer R. Martin, Nicholas G. Medland, Sarah E. Montgomery, Grant W. Willemsen, Gonneke Bartels, Meike van Beijsterveldt, Catharina E. M. Franz, Carol E. Kremen, William S. Lyons, Michael J. Silberg, Judy L. Maes, Hermine H. Kandler, Christian Nelson, Tracy L. Whitfield, Keith E. Corley, Robin P. Huibregtse, Brooke M. Gatz, Margaret Butler, David A. Tarnoki, Adam D. Tarnoki, David L. Park, Hang A. Lee, Jooyeon Lee, Soo Ji Sung, Joohon Yokoyama, Yoshie Sørensen, Thorkild I. A. Boomsma, Dorret I. Kaprio, Jaakko Genetic and environmental variation in educational attainment: an individual-based analysis of 28 twin cohorts |
title | Genetic and environmental variation in educational attainment: an individual-based analysis of 28 twin cohorts |
title_full | Genetic and environmental variation in educational attainment: an individual-based analysis of 28 twin cohorts |
title_fullStr | Genetic and environmental variation in educational attainment: an individual-based analysis of 28 twin cohorts |
title_full_unstemmed | Genetic and environmental variation in educational attainment: an individual-based analysis of 28 twin cohorts |
title_short | Genetic and environmental variation in educational attainment: an individual-based analysis of 28 twin cohorts |
title_sort | genetic and environmental variation in educational attainment: an individual-based analysis of 28 twin cohorts |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7391756/ https://www.ncbi.nlm.nih.gov/pubmed/32728164 http://dx.doi.org/10.1038/s41598-020-69526-6 |
work_keys_str_mv | AT silventoinenkarri geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT jelenkovicaline geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT sundreijo geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT latvalaantti geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT hondachika geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT inuifujio geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT tomizawarie geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT watanabemikio geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT sakainorio geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT rebatoesther geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT busjahnandreas geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT tylerjessica geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT hopperjohnl geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT ordonanajuanr geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT sanchezromerajuanf geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT colodrocondelucia geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT calaisferreiralucas geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT oliveiraviniciusc geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT ferreirapauloh geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT meddaemanuela geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT nisticolorenza geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT toccacelivirgilia geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT deromcatherinea geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT vlietinckrobertf geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT loosruthjf geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT siribaddanasisirah geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT hotopfmatthew geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT sumathipalaathula geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT rijsdijkfruhling geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT duncanglene geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT buchwalddedra geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT tyneliusper geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT rasmussenfinn geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT tanqihua geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT zhangdongfeng geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT pangzengchang geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT magnussonpatrikke geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT pedersennancyl geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT dahlaslanannak geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT hwangamiee geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT mackthomasm geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT kruegerrobertf geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT mcguematt geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT pahlenshandell geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT brandtingunn geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT nilsenthomass geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT harrisjenniferr geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT martinnicholasg geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT medlandsarahe geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT montgomerygrantw geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT willemsengonneke geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT bartelsmeike geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT vanbeijsterveldtcatharinaem geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT franzcarole geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT kremenwilliams geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT lyonsmichaelj geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT silbergjudyl geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT maeshermineh geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT kandlerchristian geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT nelsontracyl geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT whitfieldkeithe geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT corleyrobinp geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT huibregtsebrookem geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT gatzmargaret geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT butlerdavida geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT tarnokiadamd geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT tarnokidavidl geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT parkhanga geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT leejooyeon geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT leesooji geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT sungjoohon geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT yokoyamayoshie geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT sørensenthorkildia geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT boomsmadorreti geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts AT kapriojaakko geneticandenvironmentalvariationineducationalattainmentanindividualbasedanalysisof28twincohorts |