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Genetic and environmental variation in educational attainment: an individual-based analysis of 28 twin cohorts

We investigated the heritability of educational attainment and how it differed between birth cohorts and cultural–geographic regions. A classical twin design was applied to pooled data from 28 cohorts representing 16 countries and including 193,518 twins with information on educational attainment at...

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Autores principales: Silventoinen, Karri, Jelenkovic, Aline, Sund, Reijo, Latvala, Antti, Honda, Chika, Inui, Fujio, Tomizawa, Rie, Watanabe, Mikio, Sakai, Norio, Rebato, Esther, Busjahn, Andreas, Tyler, Jessica, Hopper, John L., Ordoñana, Juan R., Sánchez-Romera, Juan F., Colodro-Conde, Lucia, Calais-Ferreira, Lucas, Oliveira, Vinicius C., Ferreira, Paulo H., Medda, Emanuela, Nisticò, Lorenza, Toccaceli, Virgilia, Derom, Catherine A., Vlietinck, Robert F., Loos, Ruth J. F., Siribaddana, Sisira H., Hotopf, Matthew, Sumathipala, Athula, Rijsdijk, Fruhling, Duncan, Glen E., Buchwald, Dedra, Tynelius, Per, Rasmussen, Finn, Tan, Qihua, Zhang, Dongfeng, Pang, Zengchang, Magnusson, Patrik K. E., Pedersen, Nancy L., Dahl Aslan, Anna K., Hwang, Amie E., Mack, Thomas M., Krueger, Robert F., McGue, Matt, Pahlen, Shandell, Brandt, Ingunn, Nilsen, Thomas S., Harris, Jennifer R., Martin, Nicholas G., Medland, Sarah E., Montgomery, Grant W., Willemsen, Gonneke, Bartels, Meike, van Beijsterveldt, Catharina E. M., Franz, Carol E., Kremen, William S., Lyons, Michael J., Silberg, Judy L., Maes, Hermine H., Kandler, Christian, Nelson, Tracy L., Whitfield, Keith E., Corley, Robin P., Huibregtse, Brooke M., Gatz, Margaret, Butler, David A., Tarnoki, Adam D., Tarnoki, David L., Park, Hang A., Lee, Jooyeon, Lee, Soo Ji, Sung, Joohon, Yokoyama, Yoshie, Sørensen, Thorkild I. A., Boomsma, Dorret I., Kaprio, Jaakko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7391756/
https://www.ncbi.nlm.nih.gov/pubmed/32728164
http://dx.doi.org/10.1038/s41598-020-69526-6
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author Silventoinen, Karri
Jelenkovic, Aline
Sund, Reijo
Latvala, Antti
Honda, Chika
Inui, Fujio
Tomizawa, Rie
Watanabe, Mikio
Sakai, Norio
Rebato, Esther
Busjahn, Andreas
Tyler, Jessica
Hopper, John L.
Ordoñana, Juan R.
Sánchez-Romera, Juan F.
Colodro-Conde, Lucia
Calais-Ferreira, Lucas
Oliveira, Vinicius C.
Ferreira, Paulo H.
Medda, Emanuela
Nisticò, Lorenza
Toccaceli, Virgilia
Derom, Catherine A.
Vlietinck, Robert F.
Loos, Ruth J. F.
Siribaddana, Sisira H.
Hotopf, Matthew
Sumathipala, Athula
Rijsdijk, Fruhling
Duncan, Glen E.
Buchwald, Dedra
Tynelius, Per
Rasmussen, Finn
Tan, Qihua
Zhang, Dongfeng
Pang, Zengchang
Magnusson, Patrik K. E.
Pedersen, Nancy L.
Dahl Aslan, Anna K.
Hwang, Amie E.
Mack, Thomas M.
Krueger, Robert F.
McGue, Matt
Pahlen, Shandell
Brandt, Ingunn
Nilsen, Thomas S.
Harris, Jennifer R.
Martin, Nicholas G.
Medland, Sarah E.
Montgomery, Grant W.
Willemsen, Gonneke
Bartels, Meike
van Beijsterveldt, Catharina E. M.
Franz, Carol E.
Kremen, William S.
Lyons, Michael J.
Silberg, Judy L.
Maes, Hermine H.
Kandler, Christian
Nelson, Tracy L.
Whitfield, Keith E.
Corley, Robin P.
Huibregtse, Brooke M.
Gatz, Margaret
Butler, David A.
Tarnoki, Adam D.
Tarnoki, David L.
Park, Hang A.
Lee, Jooyeon
Lee, Soo Ji
Sung, Joohon
Yokoyama, Yoshie
Sørensen, Thorkild I. A.
Boomsma, Dorret I.
Kaprio, Jaakko
author_facet Silventoinen, Karri
Jelenkovic, Aline
Sund, Reijo
Latvala, Antti
Honda, Chika
Inui, Fujio
Tomizawa, Rie
Watanabe, Mikio
Sakai, Norio
Rebato, Esther
Busjahn, Andreas
Tyler, Jessica
Hopper, John L.
Ordoñana, Juan R.
Sánchez-Romera, Juan F.
Colodro-Conde, Lucia
Calais-Ferreira, Lucas
Oliveira, Vinicius C.
Ferreira, Paulo H.
Medda, Emanuela
Nisticò, Lorenza
Toccaceli, Virgilia
Derom, Catherine A.
Vlietinck, Robert F.
Loos, Ruth J. F.
Siribaddana, Sisira H.
Hotopf, Matthew
Sumathipala, Athula
Rijsdijk, Fruhling
Duncan, Glen E.
Buchwald, Dedra
Tynelius, Per
Rasmussen, Finn
Tan, Qihua
Zhang, Dongfeng
Pang, Zengchang
Magnusson, Patrik K. E.
Pedersen, Nancy L.
Dahl Aslan, Anna K.
Hwang, Amie E.
Mack, Thomas M.
Krueger, Robert F.
McGue, Matt
Pahlen, Shandell
Brandt, Ingunn
Nilsen, Thomas S.
Harris, Jennifer R.
Martin, Nicholas G.
Medland, Sarah E.
Montgomery, Grant W.
Willemsen, Gonneke
Bartels, Meike
van Beijsterveldt, Catharina E. M.
Franz, Carol E.
Kremen, William S.
Lyons, Michael J.
Silberg, Judy L.
Maes, Hermine H.
Kandler, Christian
Nelson, Tracy L.
Whitfield, Keith E.
Corley, Robin P.
Huibregtse, Brooke M.
Gatz, Margaret
Butler, David A.
Tarnoki, Adam D.
Tarnoki, David L.
Park, Hang A.
Lee, Jooyeon
Lee, Soo Ji
Sung, Joohon
Yokoyama, Yoshie
Sørensen, Thorkild I. A.
Boomsma, Dorret I.
Kaprio, Jaakko
author_sort Silventoinen, Karri
collection PubMed
description We investigated the heritability of educational attainment and how it differed between birth cohorts and cultural–geographic regions. A classical twin design was applied to pooled data from 28 cohorts representing 16 countries and including 193,518 twins with information on educational attainment at 25 years of age or older. Genetic factors explained the major part of individual differences in educational attainment (heritability: a(2) = 0.43; 0.41–0.44), but also environmental variation shared by co-twins was substantial (c(2) = 0.31; 0.30–0.33). The proportions of educational variation explained by genetic and shared environmental factors did not differ between Europe, North America and Australia, and East Asia. When restricted to twins 30 years or older to confirm finalized education, the heritability was higher in the older cohorts born in 1900–1949 (a(2) = 0.44; 0.41–0.46) than in the later cohorts born in 1950–1989 (a(2) = 0.38; 0.36–0.40), with a corresponding lower influence of common environmental factors (c(2) = 0.31; 0.29–0.33 and c(2) = 0.34; 0.32–0.36, respectively). In conclusion, both genetic and environmental factors shared by co-twins have an important influence on individual differences in educational attainment. The effect of genetic factors on educational attainment has decreased from the cohorts born before to those born after the 1950s.
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spelling pubmed-73917562020-07-31 Genetic and environmental variation in educational attainment: an individual-based analysis of 28 twin cohorts Silventoinen, Karri Jelenkovic, Aline Sund, Reijo Latvala, Antti Honda, Chika Inui, Fujio Tomizawa, Rie Watanabe, Mikio Sakai, Norio Rebato, Esther Busjahn, Andreas Tyler, Jessica Hopper, John L. Ordoñana, Juan R. Sánchez-Romera, Juan F. Colodro-Conde, Lucia Calais-Ferreira, Lucas Oliveira, Vinicius C. Ferreira, Paulo H. Medda, Emanuela Nisticò, Lorenza Toccaceli, Virgilia Derom, Catherine A. Vlietinck, Robert F. Loos, Ruth J. F. Siribaddana, Sisira H. Hotopf, Matthew Sumathipala, Athula Rijsdijk, Fruhling Duncan, Glen E. Buchwald, Dedra Tynelius, Per Rasmussen, Finn Tan, Qihua Zhang, Dongfeng Pang, Zengchang Magnusson, Patrik K. E. Pedersen, Nancy L. Dahl Aslan, Anna K. Hwang, Amie E. Mack, Thomas M. Krueger, Robert F. McGue, Matt Pahlen, Shandell Brandt, Ingunn Nilsen, Thomas S. Harris, Jennifer R. Martin, Nicholas G. Medland, Sarah E. Montgomery, Grant W. Willemsen, Gonneke Bartels, Meike van Beijsterveldt, Catharina E. M. Franz, Carol E. Kremen, William S. Lyons, Michael J. Silberg, Judy L. Maes, Hermine H. Kandler, Christian Nelson, Tracy L. Whitfield, Keith E. Corley, Robin P. Huibregtse, Brooke M. Gatz, Margaret Butler, David A. Tarnoki, Adam D. Tarnoki, David L. Park, Hang A. Lee, Jooyeon Lee, Soo Ji Sung, Joohon Yokoyama, Yoshie Sørensen, Thorkild I. A. Boomsma, Dorret I. Kaprio, Jaakko Sci Rep Article We investigated the heritability of educational attainment and how it differed between birth cohorts and cultural–geographic regions. A classical twin design was applied to pooled data from 28 cohorts representing 16 countries and including 193,518 twins with information on educational attainment at 25 years of age or older. Genetic factors explained the major part of individual differences in educational attainment (heritability: a(2) = 0.43; 0.41–0.44), but also environmental variation shared by co-twins was substantial (c(2) = 0.31; 0.30–0.33). The proportions of educational variation explained by genetic and shared environmental factors did not differ between Europe, North America and Australia, and East Asia. When restricted to twins 30 years or older to confirm finalized education, the heritability was higher in the older cohorts born in 1900–1949 (a(2) = 0.44; 0.41–0.46) than in the later cohorts born in 1950–1989 (a(2) = 0.38; 0.36–0.40), with a corresponding lower influence of common environmental factors (c(2) = 0.31; 0.29–0.33 and c(2) = 0.34; 0.32–0.36, respectively). In conclusion, both genetic and environmental factors shared by co-twins have an important influence on individual differences in educational attainment. The effect of genetic factors on educational attainment has decreased from the cohorts born before to those born after the 1950s. Nature Publishing Group UK 2020-07-29 /pmc/articles/PMC7391756/ /pubmed/32728164 http://dx.doi.org/10.1038/s41598-020-69526-6 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Silventoinen, Karri
Jelenkovic, Aline
Sund, Reijo
Latvala, Antti
Honda, Chika
Inui, Fujio
Tomizawa, Rie
Watanabe, Mikio
Sakai, Norio
Rebato, Esther
Busjahn, Andreas
Tyler, Jessica
Hopper, John L.
Ordoñana, Juan R.
Sánchez-Romera, Juan F.
Colodro-Conde, Lucia
Calais-Ferreira, Lucas
Oliveira, Vinicius C.
Ferreira, Paulo H.
Medda, Emanuela
Nisticò, Lorenza
Toccaceli, Virgilia
Derom, Catherine A.
Vlietinck, Robert F.
Loos, Ruth J. F.
Siribaddana, Sisira H.
Hotopf, Matthew
Sumathipala, Athula
Rijsdijk, Fruhling
Duncan, Glen E.
Buchwald, Dedra
Tynelius, Per
Rasmussen, Finn
Tan, Qihua
Zhang, Dongfeng
Pang, Zengchang
Magnusson, Patrik K. E.
Pedersen, Nancy L.
Dahl Aslan, Anna K.
Hwang, Amie E.
Mack, Thomas M.
Krueger, Robert F.
McGue, Matt
Pahlen, Shandell
Brandt, Ingunn
Nilsen, Thomas S.
Harris, Jennifer R.
Martin, Nicholas G.
Medland, Sarah E.
Montgomery, Grant W.
Willemsen, Gonneke
Bartels, Meike
van Beijsterveldt, Catharina E. M.
Franz, Carol E.
Kremen, William S.
Lyons, Michael J.
Silberg, Judy L.
Maes, Hermine H.
Kandler, Christian
Nelson, Tracy L.
Whitfield, Keith E.
Corley, Robin P.
Huibregtse, Brooke M.
Gatz, Margaret
Butler, David A.
Tarnoki, Adam D.
Tarnoki, David L.
Park, Hang A.
Lee, Jooyeon
Lee, Soo Ji
Sung, Joohon
Yokoyama, Yoshie
Sørensen, Thorkild I. A.
Boomsma, Dorret I.
Kaprio, Jaakko
Genetic and environmental variation in educational attainment: an individual-based analysis of 28 twin cohorts
title Genetic and environmental variation in educational attainment: an individual-based analysis of 28 twin cohorts
title_full Genetic and environmental variation in educational attainment: an individual-based analysis of 28 twin cohorts
title_fullStr Genetic and environmental variation in educational attainment: an individual-based analysis of 28 twin cohorts
title_full_unstemmed Genetic and environmental variation in educational attainment: an individual-based analysis of 28 twin cohorts
title_short Genetic and environmental variation in educational attainment: an individual-based analysis of 28 twin cohorts
title_sort genetic and environmental variation in educational attainment: an individual-based analysis of 28 twin cohorts
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7391756/
https://www.ncbi.nlm.nih.gov/pubmed/32728164
http://dx.doi.org/10.1038/s41598-020-69526-6
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